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Pitx2tm4(cre)Jfm - Head
Recombinase Activity Detail
Allele Information
Allele:
Pitx2tm4(cre)Jfm
paired-like homeodomain transcription factor 2; targeted mutation 4, James F Martin 		Driver: Pitx2
Type: Targeted (Recombinase)
Synonym: delta abccreneo, Pitx2-Cre, Pitx2creneo, Pitx2 delta abccreneo
Molecular description: Exon 5, which encodes a portion of the homeodomain, was disrupted by the insertion of a cassette containing IRES, cre recombinase, lacZ, and neo. In situ hybridization results showed that the expression pattern of cre was similar to that of the endogenous gene. The neo was removed by crossing to Flp-expressing mice.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Pitx2tm4(cre)Jfm activity also observed in:
cardiovascular system, muscle, nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:310423 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 32 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory