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Tg(KRT14-cre)1Amc - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(KRT14-cre)1Amc
transgene insertion 1, Andrew P McMahon 		Driver: KRT14
Type: Transgenic (Recombinase)
Synonym: K14 cre, K14-cre, K14cre, K14Cre, Krt14Cre, Krt14Cre
Molecular description: The transgene is composed of a cre recombinase gene under the control of a human keratin 14 promoter. The human KRT14 promoter directs transgene expression in hair and skin. The transgene also contains a human growth hormone sequence and polyadenylation signal. When crossed to a transgenic reporter line, beta-galactosidase activity was detected in the oral ectoderm at 11.75 dpc, and at 14.5 dpc activity is detected in the skin and throughout the dental epithelium.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(KRT14-cre)1Amc activity also observed in:
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Images
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J:184579 Full Image
Fig. KRT14 Embryo 1 E15.5 J:184579 Full Image
Fig. KRT14 Embryo 2 E15.5 J:184579 Full Image
Fig. KRT14 Skin P56 J:283206 Fig. S7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 392 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory