Tg(BGLAP-cre)1Clem - Cardiovascular System Recombinase Activity Detail MGI Mouse

Tg(BGLAP-cre)1Clem - Cardiovascular System
Recombinase Activity Detail

Allele Information | Images | Recombinase Activity | References

Allele Information

Allele:

Tg(BGLAP-cre)1Clem
transgene insertion 1, Thomas L Clemens

Driver: BGLAP
Type: Transgenic (Recombinase)

Synonym:

HOC-cre, OC-cre, OC-cre line 6, OCNCre, osteocalcin-Cre

Molecular description:

A human osteocalcin (BGLAP) promoter, driving expression in osteoblasts, fused to a cre recombinase gene was used for the transgene. The cre gene was modified to include a nuclear localization signal and human ACTB 3' untranslated region. Two lines were generated, 4 and 6. This allele represents line 6. Transgene expression was observed in the calvaria, femur, and vertebrae by Northern blot analysis.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Tg(BGLAP-cre)1Clem activity also observed in:
head, skeletal system

Images

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J:80190 Fig. 2

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

153 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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