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Tg(Gata1-cre)1Sho - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Gata1-cre)1Sho
transgene insertion 1, Stuart Orkin 		Driver: Gata1
Type: Transgenic (Recombinase)
Synonym: GATA1-Cre
Molecular description: Sequence encoding cre recombinase was adjoined to the murine Gata1 promoter region. The expanded expression pattern (relative to the endogenous Gata1 gene) has been attributed to leaky cre expression during an early stage of embryogenesis. While the Gata1 promoter was putatively a hematopoietic-specific promoter, efficient cre mediated excision has been observed in germ cells.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Gata1-cre)1Sho activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 26 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory