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Tg(KRT14-cre/ERT)20Efu - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(KRT14-cre/ERT)20Efu
transgene insertion 20, Elaine Fuchs 		Driver: KRT14
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: K14CREER, K14-CreERT, K14-CreERtam, K14CreERTam, Ker14-CreERT, Tg(KRT14-cre/Esr1)2Efu
Molecular description: Expression of a tamoxifen-inducible form of a Cre recombinase and estrogen receptor fusion protein in the basal layer of the epidermis, the outer root sheath of the hair follicle and the oral epithelium, driven by the human keratin 14 promoter (KRT14). The promoter is active by embryonic day 14.5 (E14.5).
Find mice (IMSR): Mouse Strains: 3 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(KRT14-cre/ERT)20Efu activity also observed in:
cardiovascular system, reproductive system
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Images
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J:184579 Full Image
Fig. KRT14ESR Skin HF 1 P56 J:184579 Full Image
Fig. KRT14ESR Skin HF P56 J:303437 Fig. 2 J:56822 Fig. 2 J:56822 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 218 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory