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Tg(Wnt1-cre/Esr1*)10Rth - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Wnt1-cre/Esr1*)10Rth
transgene insertion 10, David H Rowitch 		Driver: Wnt1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Tg(Wnt1-cre/Esr1)10Rth
Molecular description: This transgene expresses a tamoxifen-inducible form of a Cre recombinase/estrogen receptor fusion protein. The Wnt1 regulatory sequences initially direct expression in the midbrain. After neural tube closure, expression occurs in the dorsal and ventral midlines of the midbrain and caudal diencephalon, the midbrain-hindbrain junction and in the dorsal spinal cord.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Wnt1-cre/Esr1*)10Rth activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory