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Tg(tetO-cre)LC1Bjd - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(tetO-cre)LC1Bjd
transgene insertion LC1, Hermann Bujard 		Driver: tetO
Type: Transgenic (Inducible, Recombinase)
Inducer: doxycycline/tetracycline
Synonym: LC-1, LC1-Cre, TgLC1, TRE-LC1
Molecular description: The transgenic construct contained a bidirectional tTA/rtTA responsive promoter derived from the human cytomegalovirus promoter IE and flanked by sequence encoding luciferase and cre recombinase. Efficient cre mediated recombination, unaffected by position effect variegation, was demonstrated in hepatocytes. Transcription of in both directions was shown to be activated by rtTA in the presence of doxycycline. Transgene insertion is on chromosome 6C1 flanked by genes coding for the vomeronasal receptors V1rc14 and V1rc15 (K.Schonig, pers. commun.)
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(tetO-cre)LC1Bjd activity also observed in:
head, liver & biliary system, nervous system, respiratory system
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 137 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory