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Commd10Tg(Vav1-icre)A2Kio - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Commd10Tg(Vav1-icre)A2Kio
COMM domain containing 10; transgene insertion A2, Dimitris Kioussis 		Driver: Vav1
Type: Transgenic (Null/knockout, Recombinase)
Synonym: Tg(Vav1-cre)1Kio, Tg(Vav1-cre)A2Kio, Tg(Vav1-icre)A2Kio, Vav1-Cre, Vav1 (HS21/5)-iCre, Vav-cre, VavCre, VavCredeBoer, Vav-iCre
Molecular description: This transgene expresses Cre recombinase under the control of a vav promoter. This promoter was shown to be active in lymph nodes, thymus, spleen, Peyer's patches, intestinal cryptopatches, ovaries and testes. Line A2 inserted into the gene at 47022629-47022630 (Build GRCm38/mm10). The insetion results in a functional knock-out in homozygous mice.
Find mice (IMSR): Mouse Strains: 3 strains available       Cell Lines: 0 lines available
Additional Tissues: Commd10Tg(Vav1-icre)A2Kio activity also observed in:
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Images
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J:193672 Full Image
Fig. Vav1 Br Fat P56 J:193672 Full image
Fig. Vav1 Br Fat P7 J:193672 Full Image
Fig. Vav1 Skin P56 J:193672 Full Image
Fig. Vav1 Skin P7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 579 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory