Commd10<Tg(Vav1-icre)A2Kio> - Limbs Recombinase Activity Detail MGI Mouse

Commd10^{Tg(Vav1-icre)A2Kio} - Limbs
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Commd10^{Tg(Vav1-icre)A2Kio}
COMM domain containing 10; transgene insertion A2, Dimitris Kioussis

Driver: Vav1
Type: Transgenic (Null/knockout, Recombinase)

Synonym:

Tg(Vav1-cre)1Kio, Tg(Vav1-cre)A2Kio, Tg(Vav1-icre)A2Kio, Vav1-Cre, Vav1 (HS21/5)-iCre, Vav-cre, VavCre, VavCre^deBoer, Vav-iCre

Molecular description:

This transgene expresses Cre recombinase under the control of a vav promoter. This promoter was shown to be active in lymph nodes, thymus, spleen, Peyer's patches, intestinal cryptopatches, ovaries and testes. Line A2 inserted into the gene at 47022629-47022630 (Build GRCm38/mm10). The insetion results in a functional knock-out in homozygous mice.

Find mice (IMSR):

Mouse Strains: 3 strains available Cell Lines: 0 lines available

Additional Tissues:

Commd10^{Tg(Vav1-icre)A2Kio} activity also observed in:

adipose tissue, alimentary system, cardiovascular system, endocrine system ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

580 reference(s)

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