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Tg(KRT18-cre/ERT2)1Rgo - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(KRT18-cre/ERT2)1Rgo
transgene insertion 1, Robert G Oshima
Driver: KRT18
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: K18CreER, K18iresCreERT2
Molecular description: The transgenic construct encodes a tamoxifen-inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand-binding domain inserted into exon 7 of human KRT18. Human KRT18 regulatory sequences were used to drive transgene expression in epithelial cells.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(KRT18-cre/ERT2)1Rgo activity also observed in:
integumental system, liver & biliary system, nervous system, renal & urinary system, reproductive system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory