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Plekha5Tg(AMH-cre)1Flor - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Plekha5Tg(AMH-cre)1Flor
pleckstrin homology domain containing, family A member 5; transgene insertion 1, Florian Guillou 		Driver: AMH
Type: Transgenic (No functional change, Recombinase)
Synonym: AMH-Cre, Mis-Cre, Tg(AMH-cre)1Flor
Molecular description: The transgene consists of a human AMH promoter, a cre recombinase gene, and genomic sequences from MT1 to provide mRNA secondary structure stability. The gene trap inserted into intron 3. Northern blot analysis shows gonad-specific transgene expression in Sertoli cells of 6 day old male mice and granulosa cells of 16 day old female mice. RT-PCR confirmed normal endogenous gene expression. The insertion site of the original cre transgene was subsequenly identified as intron 3 of Plekha5.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Plekha5Tg(AMH-cre)1Flor activity also observed in:
reproductive system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:81650 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 130 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory