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Tg(Tek-cre)1Ywa - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tek-cre)1Ywa
transgene insertion 1, Masashi Yanagisawa 		Driver: Tek
Type: Transgenic (Hypomorph, Recombinase)
Synonym: T2Cre, TekCre, Tie-2 Cre, Tie2-Cre, Tie2Cre, Tie2Cre+
Molecular description: This transgene expresses Cre recombinase under the control of a mouse Tek promoter and enhancer. This promoter is active in endothelial cells. Insertion within intron 1 of Sorcs2 results in the 204 bp deletion (36382105 to 36382309 on mouse chromosome 5; GRCm37/mm9 genome build) leading to reduced and variable expression.
Find mice (IMSR): Mouse Strains: 6 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tek-cre)1Ywa activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:193672 Full Image
Fig. Tek Brain P7 J:193672 Full Image
Fig. Tek Cereb Cort P56 J:193672 Full Image
Fig. Tek Cerebellum P56 J:193672 Full Image
Fig. Tek Cerebellum P7 J:193672 Full Image
Fig. Tek Cerebral Cort E15.5 J:193672 Full Image
Fig. Tek Choroid Plexus P56 J:193672 Full Image
Fig. Tek Cranial Ganglia E15.5 J:193672 Full Image
Fig. Tek DRG E15.5
J:193672 Full Image
Fig. Tek Eye Optic Nerve P7 J:193672 Full Image
Fig. Tek Hippocampus P56 J:193672 Full Image
Fig. Tek Hypothalamus P56 J:193672 Full Image
Fig. Tek Medulla E15.5 J:193672 Full Image
Fig. Tek Olfactory Lobe P56 J:193672 Full Image
Fig. Tek Olfactory Lobe P7 J:193672 Full Image
Fig. Tek Pituitary P56 J:193672 Full Image
Fig. Tek Pons/Medulla P56
J:193672 Full Image
Fig. Tek Pons/Medulla P7 J:193672 Full Image
Fig. Tek Sp Cord (cerv) P7 J:193672 Full Image
Fig. Tek Sp Cord E15.5 J:193672 Full Image
Fig. Tek Sp Cord (lumb) P7 J:193672 Full Image
Fig. Tek Sp Cord (thor) P7 J:193672 Full Image
Fig. Tek Thalamus P56 J:193672 Full Image
Fig. Tek Thalamus P7 J:193672 Full Image
Fig. Tek Thal/Hypothal E15.5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 776 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory