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Tg(Prrx1-cre)1Cjt - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Prrx1-cre)1Cjt
transgene insertion 1, Clifford J Tabin 		Driver: Prrx1
Type: Transgenic (Recombinase)
Synonym: Prx1-cre, Prx1cre, Prx-1 Cre, Prx1Cre, Prx-cre, Tg[Prx1-cre]1Cjt
Molecular description: This transgene expresses Cre recombinase under the control of a Prrx1 derived enhancer. This transgene is expressed in the early limb bud mesenchyme and in a subset of craniofacial mesenchyme. A germline Cre recombinase activity was observed in female, but not in male, as partially penetrant trait depending on the particular gene flanked by loxP sites.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Prrx1-cre)1Cjt activity also observed in:
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Images
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J:216865 Full Image
Fig. Prrx1 Adult Bone J:216865 Full Image
Fig. Prrx1 E15.5 Arm J:216865 Full Image
Fig. Prrx1 E15.5 Cranium J:216865 Full Image
Fig. Prrx1 E15.5 Lower jaw J:216865 Full Image
Fig. Prrx1 E15.5 Rib
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 491 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory