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Nkx2-5tm1(cre)Rjs - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Nkx2-5tm1(cre)Rjs
NK2 homeobox 5; targeted mutation 1, Robert J Schwartz
Driver: Nkx2-5
Type: Targeted (Recombinase)
Synonym: Nkx2.5cre, Nkx2-5/Cre, Nkx2-5Cre, Nkx2.5-Cre
Molecular description: A cre recombinase gene followed by a neomycin selection cassette was inserted in-frame into exon 2. Reporter expression assays indicated that an active fusion protein was expressed from this allele in the embryonic heart, tongue, thymus and spleen.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Nkx2-5tm1(cre)Rjs activity also observed in:
branchial arches, cardiovascular system, embryo-other, head, hemolymphoid system, muscle
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:73654 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 155 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory