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Tg(Foxa3-cre)1Khk - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Foxa3-cre)1Khk
transgene insertion 1, Klaus H Kaestner 		Driver: Foxa3
Type: Transgenic (Recombinase)
Synonym: Foxa3.cre, Foxa3-Cre, Foxa3cre, Foxa3Cre, Tg(Foxa3-cre)1Khk
Molecular description: The transgenic construct consists of a 170 kb fragment containing a modified Foxa3 locus in which exon 2 has been replaced with an IRES-cre cassette. Cre activity was first detected 8.5 dpc in the anterior intestinal portal, and later in the entire gut endoderm from stomach to colon. Efficient cre-mediated recombination was demonstrated in the stomach, liver, pancreas, and colon.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Foxa3-cre)1Khk activity also observed in:
extraembryonic component, mesenchyme, tail
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:96332 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 37 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory