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Tg(Hoxb7-cre)13Amc - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Hoxb7-cre)13Amc
transgene insertion 13, Andrew P McMahon 		Driver: Hoxb7
Type: Transgenic (Recombinase)
Synonym: Hoxb7-Cre, HoxB7/Cre, HoxB7Cre
Molecular description: A transgenic construct containing the 1.3Kb enhancer and promoter sequence upstream of the of mouse homeo box B7 gene, a human growth factor mini gene and the Cre coding sequence was injected into fertilized C57BL/6 mouse eggs. Cre recombinase expression is detected in the mesonephric duct as early as embryonic day 9.5, in the ureteric bud by embryonic day 10.25 and in all ureteric bud epithelial cells by embryonic day 12.5. Low levels of expression are detected in the dorsal root ganglia and the spinal cord.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Hoxb7-cre)13Amc activity also observed in:
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
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J:137524 Fig. 1 J:137887 Fig. Hoxb7 Embryo 2a E10.5 J:137887 Fig. Hoxb7 Embryo 2 E10.5 J:137887 Fig. Hoxb7 Embryo 4 E0.5 J:137887 Fig. Hoxb7 Embryo E10.5 J:137887 Fig. Hoxb7 Epididymis Adult J:137887 Fig. Hoxb7 Epididymis Adult J:137887 Fig. Hoxb7 Testis 2 Adult
J:137887 Fig. Hoxb7 Testis a P7 J:137887 Fig. Hoxb7 Testis P7 J:137887 Fig. Hoxb7 Uterus 2 Adult J:137887 Fig. Hoxb7 Uterus Adult J:79481 Fig. 2 J:98831 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 115 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory