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Tg(Th-cre)12Mrub - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Th-cre)12Mrub
transgene insertion 12, Marcelo Rubinstein 		Driver: Th
Type: Transgenic (Recombinase)
Synonym: TH-Cre
Molecular description: Sequence encoding cre recombinase was adjpoined to 9 kb of the rat tyrosine hydroxylase (Th) promoter. The rat Th promoter sequence drove expression of cre recombinase in catecholaminergic neurons. Expression was observed in the olfactory bulb, hypothalamic and midbrain dopaminergic neurons, the locus coeruleus, amacrime neurons of the retina, chromaffin cells of the adrenal medulla, and sympathetic ganglia.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Th-cre)12Mrub activity also observed in:
endocrine system, head, sensory organs
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:85520 Fig. 1 J:85520 Fig. 2 J:85520 Fig. 3 J:85520 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 13 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory