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Tg(Pdx1-cre)89.1Dam - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pdx1-cre)89.1Dam
transgene insertion 89.1, Douglas A Melton 		Driver: Pdx1
Type: Transgenic (Recombinase)
Synonym: Pdx15.5-Cre, Pdx1-Cre, Pdx1Cre, Pdx1-Creearly, Pdx1-Cretg, Pdx1Tg-Cre, PDX-cre, pPdx1-Cre, Tg(Ipf1-cre)89.1Dam
Molecular description: Sequence encoding cre recombinase was adjoined to a mouse 5.5 kb region containing Pdx1 regulatory sequences. This promoter drives expression of cre recombinase in the pancreas. Expression was observed in the acini, islets, and ducts but not in mesenchymal cells (endothelial and mesenchyme-derived smooth muscle cells). Robust cre expression can be detected by E10.5 in pancreatic epithelium.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pdx1-cre)89.1Dam activity also observed in:
alimentary system, endocrine system, head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:166612 Fig. 3 J:166612 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 224 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory