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Tg(Neurog3-cre/Esr1*)1Dam - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Neurog3-cre/Esr1*)1Dam
transgene insertion 1, Douglas A Melton 		Driver: Neurog3
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Ngn3-Cre, Ngn3/CreERTM, Tg(Neurog3-cre/Esr1)1Dam
Molecular description: The sequence encoding a tamoxifen-inducible form of a cre recombinase/estrogen receptor fusion protein was adjoined to a 6.7 kb Neurog3 promoter fragment. The neurogenin 3 promoter drives the expression of cre recombinase in the islet cells of the pancreas.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Neurog3-cre/Esr1*)1Dam activity also observed in:
alimentary system, reproductive system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Images
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J:76095 Fig. 5 J:76095 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 19 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory