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Allele Information
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Allele:
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Emx1tm1(cre)Krj
empty spiracles homeobox 1;
targeted mutation 1, Kevin R Jones
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Driver: Emx1
Type: Targeted
(Recombinase)
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Synonym:
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emx1-cre, Emx1-Cre, Emx1Cre, Emx1IREScre, Emx1-IRES-Cre
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Molecular description:
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An IRES-cre gene followed by an FRT flanked PGK-neomycin gene was inserted 120 bp 3' of the stop codon. The neomycin gene was later removed in vivo by crossing to an Flp recombinase expressing transgenic strain. The protein product of this gene was produced in normal quantities as confirmed by Western blot analysis. Cre recombinase expression was characterized by crossing to a Rosa26 strain.
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Find mice (IMSR):
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Mouse Strains:
2
strains available
Cell Lines:
0 lines available
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Additional Tissues:
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Emx1tm1(cre)Krj activity also observed in:
alimentary system,
branchial arches,
embryo-other,
head,
hemolymphoid system,
integumental system,
mesenchyme,
muscle,
nervous system,
renal & urinary system,
sensory organs
(less)
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Tissue Information
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Limbs
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Other recombinase alleles with activity in Limbs tissues:
Acanem2(dre)Smoc,
Acantm1(cre/ERT2)Crm,
Alpltm1(cre)Nagy,
Cacna1htm2.1(cre)Glwn,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cdkn1aem3(cre/ERT)Smoc,
Clec11aem3(cre/ERT2)Sjm,
Clutm2(EGFP/cre/ERT2)Wtsi,
Col10a1em1(cre)Bcgen,
Col10a1tm2.1(cre)Ksec,
Col10a1tm3.1(cre/ERT)Ksec,
Col2a1em2(dre)Smoc,
Crybb1em1(icre)Cln,
Ddx4em1(icre)Jobo,
Dmp1tm1(cre)Msue,
E2f1Tg(Wnt1-cre)2Sor,
En1tm2(cre)Wrst,
Etv5tm1(cre/ERT2)Brst,
Fgf10tm2.1(cre/ERT2)Sbel,
Fgf16tm1.1(cre)Sms,
Fgf18tm2.2(cre/ERT2)Dor,
Fgf8tm3.1(cre/Esr1*)Moon,
Foxg1tm1(cre)Skm,
Gas1em1(icre/ERT2)Nono,
Gli1tm3(cre/ERT2)Alj,
Gt(ROSA)26Sortm1(FLP1)Dym,
H2az2Tg(Wnt1-cre)11Rth,
Hand2em1(dre)Pjen,
HhatTg(TFAP2A-cre)1Will,
Hic1tm2.1(cre/ERT2)Tmun,
Hoxa11em1(cre/ERT2)Dmwe,
Hoxa13tm1.1(cre/ERT2)Mtor,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Ifi208Tg(Cspg4-cre)1Akik,
Ihhem1(Tomm20/mKate2,dre)Xya,
Islrtm2.1(cre/ERT2)Mat,
Kittm1.1(cre)Jmol,
Krt17tm1(cre)Murr,
Krt6aem1(icre)Vk,
Leprem4(dre/ERT2)Smoc,
Lhx9tm1.1(cre/ERT2)Gan,
Lmx1btm2(cre/ERT2)Rjo,
Meis1tm3.1(cre/ERT2)Mtor,
Meox1tm1(cre)Jpa,
Mnx1tm4(cre)Tmj,
Mrgprdtm1.1(cre/ERT2)Wql,
Myf5tm1.1(cre/Esr1*)Trdo,
Myf5tm1.1(cre)Mrc,
Myf5tm1(cre/Esr1*)Trdo,
Myf5tm1(cre)Mrc,
Myf5tm3(cre)Sor,
Myf6tm1.1(cre/ERT2)Lepr,
Myl1tm1.1(cre/ERT2)Lepr,
Myocdtm1(cre)Dzw,
Myocdtm1(cre)Jomm,
Myod1tm1.1(cre/ERT2)Lepr,
Myod1tm2.1(icre)Glh,
Myogtm1.1(cre/ERT2)Lepr,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Notch1tm3(cre)Rko,
Osr2tm2(cre)Jian,
Pax3tm1.1(cre/ERT2)Lepr,
Pax3tm1(cre)Joe,
Pax7tm1(cre/ERT2)Gaka,
Pax7tm1(cre/Esr1*)Cklr,
Pax7tm1(cre)Mrc,
Pax7tm2.1(cre/ERT2)Fan,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Piezo2tm1.1(cre)Apat,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Prdm1tm3(icre)Rob,
Prdm1tm5.1(cre/ERT2)Rob,
Scxtm1.1(cre)Shuk,
Shhtm1(EGFP/cre)Cjt,
Shhtm2(cre/ERT2)Cjt,
Shroom3Gt(ROSA53)Sor,
Six1tm1(cre)Xli,
Slc17a6tm2(cre)Lowl,
Sp7tm1(icre)Bcgen,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Taglntm2(cre)Yec,
Tbx3em1(cre/ERT2)Toyo,
Tcf7l1tm1.1(cre/ERT2)Hng,
Tcf7l2tm3.1(cre/ERT2)Mrc,
Tekem1(dre)Bzsh,
Tg(Acan-cre/ERT2,-luc)1Gbg,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(ACTA1-cre)1Mll,
Tg(ACTA1-cre)79Jme,
Tg(ACTA1-cre/ERT2)97.16Mtz,
Tg(ACTA1-cre/Esr1*)2Kesr,
Tg(ACTA1-rtTA,tetO-cre)102Monk,
Tg(Acta2-cre/ERT2)1Ikal,
Tg(Alx4-cre/ERT2)1Bky,
Tg(Bmx-cre/ERT2)1Rha,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Col10a1-cre)1427Vdm,
Tg(Col10a1-cre)1465Vdm,
Tg(Col10a1-cre)1466Vdm,
Tg(Col10a1-cre)1Xya,
Tg(Col10a1-cre)#Ksec,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre)2Bek,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a1-cre/Esr1*)1Mis,
Tg(Col1a1-cre)#Xya,
Tg(Col1a2-cre)23Angl,
Tg(Col1a2-cre/ERT,-ALPP)7Cpd,
Tg(Col2a1-cre)10Amc,
Tg(Col2a1-cre)15Amc,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre)1Rsjo,
Tg(Col2a1-cre)1Xya,
Tg(Col2a1-cre)3Amc,
Tg(Col2a1-cre/ERT)1Flng,
Tg(Col2a1-cre/ERT2)1Dic,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Col2a1-rtTA,tetO-cre)22Pjro,
Tg(Colq-cre)#Kohno,
Tg(Ctgf-cre)2Aibs,
Tg(Ctsk-cre)1Rda,
Tg(Ctsk-cre)8Rda,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(Dkk3-cre/ERT2)#Mpac,
Tg(Dll1-cre)33Dchp,
Tg(dlx5a-cre)1Mekk,
Tg(Dmp1-cre)1Jqfe,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Etv2-cre/ERT2)#Djg,
Tg(Fabp4-cre)1Rev,
Tgfb3tm1(cre)Vk,
Tg(Frzb-cre)1Tylz,
Tg(Gata1-icre)1Jtp,
Tg(Gdf5-cre,-ALPP)1Kng,
Tg(Gdf5-cre/ERT2)#Mpac,
Tg(GDF6-cre/ERT2)L2Kng,
Tg(Gfap-cre)73.12Mvs,
Tg(GH1-cre)1Sac,
Tg(Ghrhr-cre)3242Lsk,
Tg(Grem1-cre/ERT)3Tcw,
Tg(Hand2-cre)7-1Clou,
Tg(Hoxb6-cre/ERT)1Smac,
Tg(Hspa2-cre)1Eddy,
Tg(I12b-cre)1Jlr,
Tg(KRT14-cre)1Amc,
Tg(KRT5-cre)5132Jlj,
Tg(Lbx1-cre)3Cbm,
Tg(Lepr-cre/ERT2)#Cya,
Tg(Lepr-cre/ERT2)#Rha,
Tg(Mef2c-cre)1Blk,
Tg(mI56i-cre)6-2Clou,
Tg(Mnx1-cre/ERT2)8Rbro,
Tg(Msx2-cre)5Rem,
Tg(Msx2-cre/ERT2)2Nono,
Tg(Msx2-cre/ERT)27Alj,
Tg(Myh7-cre)1Zli,
Tg(Myl1-cre)13Nros,
Tg(MYOD1-cre)M23Glh,
Tg(Myog-cre)1Eno,
Tg(Osr1-cre)4Mrt,
Tg(Pax3-cre)2Joe,
Tg(Pdgfrb-cre/ERT2)6096Rha,
Tg(Pf4-icre)Q3Rsko,
Tg(Pitx2-cre/Esr1*)#Hmd,
Tg(Pitx3-cre/ERT2)1Yqd,
Tg(Plp1-cre/ERT2)1Ueli,
Tg(Pou3f4-cre)32Cren,
Tg(POU3F4-cre)M51Cren,
Tg(Prdm1-cre)1Masu,
Tg(Prg4-cre/ERT2)#Mpac,
Tg(Prg4-cre/ERT2)#Ndy,
Tg(Prg4-cre)#Mkaz,
Tg(Prrx1-cre)1Cjt,
Tg(Prrx1-cre/ERT2)1Mlgn,
Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka,
Tg(Pthlh-cre/ERT2)909Nono,
Tg(Rarb-cre)1Bhr,
Tg(Rarb-cre)1Mrc,
Tg(Relb-cre)53Rie,
Tg(Rr162136-cre/ERT2)#Bpou,
Tg(Rr437-cre)#Hmd,
Tg(Rr456-cre/Esr1*)7Hmd,
Tg(Runx2-icre)1Jtuc,
Tg(S100b-EGFP/cre/ERT2)22Amc,
Tg(Scx-cre)HShuk,
Tg(Scx-cre)LShuk,
Tg(Sim1-cre)1Lowl,
Tg(Six1-cre)2Kwk,
Tg(Smad7-cre)1Sjc,
Tg(Sp7-cre/ERT2)#Hmk,
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc,
Tg(Tagln-cre)1Her,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tbx18-icre)3Fech,
Tg(Tbx6-cre)#Rsam,
Tg(T-cre)1Lwd,
Tg(Tek-cre)1Ywa,
Tg(Thy1-cre)1Vln,
Tg(Tyr-cre/ERT2)13Bos,
Tg(Ure2-cre)1Jlr,
Tg(Zp3-cre)3Mrt,
Thtm1(cre)Te,
Tppp3tm1.1(icre/ERT2)Fan,
Trpv4em1(cre/ERT2)Amc,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor,
Twist2tm1(cre/ERT2)Eno,
Wt1tm1(EGFP/cre)Wtp
(less)
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Images
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Reset Images
J:184578
Full Image
Fig. Emx1 E10.5 d
J:184578
Fig. Emx1 Embryo 2 E10.5
J:184578
Fig. Emx1 Embryo E10.5
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Recombinase Activity
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Assays
Genotypic Background
Result Notes
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References
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