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Allele Information
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Allele:
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Tg(Cryaa-cre)10Mlr
transgene insertion 10, Mike Robinson
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Driver: Cryaa
Type: Transgenic
(Recombinase)
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Synonym:
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CPV14/Cre, cry-cre, Mlr10, MLR10-Cre
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Molecular description:
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The expression of sequence encoding cre recombinase was driven by a modified alpha A crystallin promoter. The promoter consists of -282/+43 of the mouse Cryaa gene with an inserted copy of Pax6 consensus binding site in a 5' to 3' orientation at position -86 of the promoter. Seven lines were created with this line having expression of the transgene in both the lens epithelium and lens fiber cells but not in other parts of the eye.
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Cryaa-cre)10Mlr activity also observed in:
head,
integumental system,
nervous system,
sensory organs
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Tissue Information
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Endocrine System
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Other recombinase alleles with activity in Endocrine System tissues:
7630403G23RikTg(Th-cre)1Tmd,
Agrptm1(cre)Lowl,
Alpltm1(cre)Nagy,
Ccktm1.1(cre)Zjh,
Cfap126tm1.1(icre)Heli,
Commd10Tg(Vav1-icre)A2Kio,
Cpa1tm1(cre/ERT2)Dam,
Crhtm1.1(flpo)Bsab,
Crhtm1(cre)Zjh,
Cx3cr1tm1.1(cre)Jung,
Cx3cr1tm2.1(cre/ERT2)Jung,
Cyp11a1tm1(GFP/cre)Pzg,
E2f1Tg(Wnt1-cre)2Sor,
Fgf16tm1.1(cre)Sms,
Foxd1tm1(GFP/cre)Amc,
Foxl2tm1(GFP/cre/ERT2)Pzg,
Gad2tm2(cre)Zjh,
Gcgem1(cre)Utr,
Gcgtm1.1(cre/ERT2)Yasu,
Ghem1(cre)Jmz,
Ghsrtm1.1(cre)Jmz,
Glp1rtm1.1(cre)Cors,
Gnao1tm2(EGFP/cre/ERT2)Wtsi,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gper1em1(cre)Smoc,
Gt(ROSA)26Sortm1.1(CAG-cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
H2az2Tg(Wnt1-cre)11Rth,
Hand2em1(dre)Pjen,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm1(TG-cre)1Sasr,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Ifi208Tg(Cspg4-cre)1Akik,
Ihhem1(Tomm20/mKate2,dre)Xya,
Ins1tm1.1(cre)Thor,
Ins1tm2.1(cre/ERT2)Thor,
Krt17tm1(cre)Murr,
Krt19tm1(cre/ERT)Ggu,
Leprtm2(cre)Rck,
Lyve1tm1.1(EGFP/cre)Cys,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx2-1tm1.1(cre/ERT2)Zjh,
Nkx2-2tm4.1(cre/EGFP)Suss,
Nkx2-5tm2(cre)Rph,
Notch1tm3(cre)Rko,
Npvftm1.1(icre)Gand,
Nxph4em1(cre)Zak,
Omptm4(cre)Mom,
Oprk1tm1.1(cre)Sros,
Osr2tm2(cre)Jian,
Oxttm1.1(icre)Ksak,
Pax3tm1(cre)Joe,
Pax7tm2.1(cre/ERT2)Fan,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdx1tm1.1(dre)Gkg,
Pdyntm1.1(cre)Mjkr,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Prlrtm1.1(cre)Uboe,
Ptf1atm1.1(cre)Cvw,
Ptf1atm1(flpo)Hcrd,
Raxtm1.1(cre/ERT2)Sbls,
Rxfp1em1(cre)Ngai,
Setd4em1(cre)Wjy,
Setd4tm2.1(cre/ERT2)Wjy,
Sfta3tm1.1(cre/ERT2)Eem,
Shhtm1(EGFP/cre)Cjt,
Shhtm2(cre/ERT2)Cjt,
Slc17a6tm2(cre)Lowl,
Slc26a9em1(cre)Sms,
Sox2tm1.1(cre/ERT2)Jpmb,
Spink1tm3(cre)Kymm,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Ssttm2.1(cre)Zjh,
Taglntm2(cre)Yec,
Tbx3em1(cre)Mhts,
Tg(ACTA1-cre)79Jme,
Tg(ACTB-cre)1Tes,
Tg(ACTFLPe)9205Dym,
Tg(Actl6b-cre)4092Jiwu,
Tg(Adipoq-cre)1Evdr,
Tg(Akr1b7-cre)1Anm,
Tg(Alb1-cre)1Dlr,
Tg(Amh-cre)8815Reb,
Tg(Amy2-cre)1Herr,
Tg(CA2-cre)1Subw,
Tg(CA2-cre/Esr1*)1Subw,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Camk2a-cre)1Nobs,
Tg(Camk2a-cre/ERT2)1Aibs,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)7Mlia,
Tg(CDX2-cre)101Erf,
Tg(Cga-cre)3Sac,
Tg(Cga-icre)961Sac,
Tg(CMV-cre)1Cgn,
Tg(Crx-cre)1Tfur,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp11a1-cre)16Mchu,
Tg(Cyp17a1-icre)AJako,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp39a1-cre)1Aibs,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Dbh-cre/ERT2)198.1Hroh,
Tg(Ddx4-cre)1Dcas,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Rev,
Tg(Fev-cre)FF9Pasq,
Tg(Gcg-cre)1Herr,
Tg(Gcg-cre)1Slib,
Tg(Gcg-icre)23Cshi,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(Gfap-cre)77.6Mvs,
Tg(GH1-cre)1Sac,
Tg(Gh1-cre)bKnmn,
Tg(Ghrhr-cre)3242Lsk,
Tg(Ghrl-cre)E7Jmz,
Tg(Ghrl-icre)#Weiz,
Tg(Glp1r-icre)#Fmgb,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Inha-cre)1Zuk,
Tg(Inha-cre)2Zuk,
Tg(Inha-cre)3Zuk,
Tg(Ins1-cre)25Utr,
Tg(Ins1-cre,-DsRed*T3)#Caoy,
Tg(Ins1-cre/ERT)1Lphi,
Tg(Ins1-cre/ERT2)#Pesch,
Tg(Ins2-cre)23Herr,
Tg(Ins2-cre)25Mgn,
Tg(Ins2-cre/ERT)1Dam,
Tg(Ins2-tTA,tetO-cre)1Ctlh,
Tg(INS-icre)18Msdr,
Tg(Itgax-cre)1-1Reiz,
Tg(Lck-icre)3779Nik,
Tg(Lhb-cre)1Sac,
Tg(LHX3-cre)#Sjr,
Tg(Mbp-cre)6Gvn,
Tg(Mbp-cre)9Gvn,
Tg(Mchr1-cre/ERT2)3Nbe,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Nes-cre)1Kln,
Tg(Neurod1-cre)1Able,
Tg(Neurog3-cre)1Dam,
Tg(NEUROG3-cre)1Herr,
Tg(Neurog3-cre)C1Able,
Tg(Neurog3-cre/ERT2)1Able,
Tg(Neurog3-cre/Esr1*)1Dam,
Tg(Nkx2-1-cre)2Sand,
Tg(NPHS2-cre)295Lbh,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Nr5a1-cre)7Lowl,
Tg(Nr5a1-cre/ERT2)4Kmor,
Tg(Pax4-cre)1Dam,
Tg(Pax6-cre)1Rilm,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pcp2-cre)2Mpin,
Tg(Pdx1-cre)1Herr,
Tg(Pdx1-cre)6Cvw,
Tg(Pdx1-cre)89.1Dam,
Tg(Pdx1-cre/Esr1*)1Mga,
Tg(Pdx1-cre/Esr1*)35.10Dam,
Tg(Pdx1-cre/Esr1*)35.6Dam,
Tg(Pdx1-cre/Esr1*)#Dam,
Tg(Pf4-icre)Q3Rsko,
Tg(Pitx1-cre)7Rsd,
Tg(Pomc1-cre)16Lowl,
Tg(Pomc-cre)5Brn,
Tg(Pomc*-cre/ERT2)#Rlb,
Tg(Pomc*-cre)#Jdr,
Tg(Pomc-dre)#Jcbr,
Tg(Prdm1-cre)1Masu,
Tg(Prl-cre)#Salr,
Tg(Prm-cre)58Og,
Tg(Prop1-cre)1Rsd,
Tg(Prop1-icre)517Sac,
Tg(Prrx1-cre)1Cjt,
Tg(PTH-cre)4167Slib,
Tg(Rarb-cre)1Bhr,
Tg(Relb-cre)53Rie,
Tg(REN-cre)1Haca,
Tg(Ren-cre)#Kwg,
Tg(Scnn1a-cre)3Aibs,
Tg(Sim1-cre)1Lowl,
Tg(Stra8-icre)1Reb,
Tg(Sycp1-cre)4Min,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)1Ywa,
Tg(tetO-cre)1Jaw,
Tg(Tg-cre)1Soff,
Tg(Tg-cre/ERT2)1Kero,
Tg(Th-cre)12Mrub,
Tg(Thy1-cre)1Vln,
Tg(TPO-cre)1Shk,
Tg(Tshb-cre)4Sac,
Tg(Tyr-cre)1Gfk,
Tg(Tyr-cre/ERT2)13Bos,
Tg(Ucp1-cre)1Evdr,
Tg(Vav1-cre)8Cgp,
Tg(Vil1-cre)997Gum,
Tg(Wfs1-cre/ERT2)3Aibs,
Thtm1(cre)Te,
Tmprss2tm1.1(cre/ERT2)Ychen,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh,
Wt1tm1(EGFP/cre)Wtp
(less)
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Recombinase Activity
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Click heading to re-sort table.
Assays
Genotypic Background
Result Notes
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References
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