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Tg(Cryaa-cre)10Mlr - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cryaa-cre)10Mlr
transgene insertion 10, Mike Robinson 		Driver: Cryaa
Type: Transgenic (Recombinase)
Synonym: CPV14/Cre, cry-cre, Mlr10, MLR10-Cre
Molecular description: The expression of sequence encoding cre recombinase was driven by a modified alpha A crystallin promoter. The promoter consists of -282/+43 of the mouse Cryaa gene with an inserted copy of Pax6 consensus binding site in a 5' to 3' orientation at position -86 of the promoter. Seven lines were created with this line having expression of the transgene in both the lens epithelium and lens fiber cells but not in other parts of the eye.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cryaa-cre)10Mlr activity also observed in:
endocrine system, head, integumental system, sensory organs
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 56 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory