About   Help   FAQ
Tg(Col1a1-cre)1Kry - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Col1a1-cre)1Kry
transgene insertion 1, Gerard Karsenty 		Driver: Col1a1
Type: Transgenic (Recombinase)
Synonym: 2.3kb alpha1(I)-cre, alpha1(1) collagen-Cre, alpha1(I)collagen-Cre, alpha1(I)-Cre, Col1a12.3kbCre, Col1-Cre, Col2.3-Cre, Col-Cre
Molecular description: Sequence encoding cre recombinase was adjoined to 2.3 kb of the Col1a1 promoter. The endogenous Col1a1 promoter is active in osteoblasts throughout their differentiation and, accordingly, expression of cre recombinase was detected exclusively in bone. Cytogenetic mapping indicates that the transgene integrated on chromosome 14qE2-4.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Col1a1-cre)1Kry activity also observed in:
head, integumental system, limbs
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:77071 Fig. 3
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 149 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory