Tbx1<tm4(cre/Esr1*)Bld> - Cardiovascular System Recombinase Activity Detail MGI Mouse

Tbx1^{tm4(cre/Esr1*)Bld} - Cardiovascular System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Tbx1^{tm4(cre/Esr1*)Bld}
T-box 1; targeted mutation 4, Antonio Baldini

Driver: Tbx1
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Tbx1^mcm, Tbx1^{tm4(cre/Esr1)Bld}

Molecular description:

An IRES and MerCreMer fusion gene were inserted into exon 5 via homologous recombination. This is the same insertion site as in Tbx1^tm1Bld. This results in tamoxifen-inducible cre expression under the control of the endogenous Tbx1 promoter.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Tbx1^{tm4(cre/Esr1*)Bld} activity also observed in:
branchial arches

Tissue Information

Cardiovascular System

Other recombinase alleles with activity in Cardiovascular System tissues:

A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Aldh1l1^{em1(cre/ERT2)Nju}, Alpl^tm1(cre)Nagy ...(more)

Images

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J:102843 Fig. 1

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

10 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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