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Tg(Cr2-cre)3Cgn - Hemolymphoid System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cr2-cre)3Cgn
transgene insertion 3, University of Cologne 		Driver: Cr2
Type: Transgenic (Recombinase)
Synonym: CD21-cre, CD21-cre3a, Cr2tm1(cre)Cgn
Molecular description: This transgene consists of a cre expression cassette including a Kozak sequence, nuclear localization signal, and bovine growth hormone polyadenylation signal inserted into a BAC containing the Cr2 locus. The ATG in the first exon of Cr2 is also mutated in this allele. Cre mediated recombination is detected in 60% - 80% of mature B cells and is undetectable in pro/pre-B and immature B cells.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Tissue Information
Hemolymphoid System Other recombinase alleles with activity in Hemolymphoid System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 78 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory