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Tg(Pax6-cre,GFP)2Pgr - Sensory Organs
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pax6-cre,GFP)2Pgr
transgene insertion 2, Peter Gruss 		Driver: Pax6
Type: Transgenic (Recombinase)
Synonym: alpha-cre, alphaP0CREiresGFP, aPax6-Cre, Pax6-aCre, Pax6-alpha-Cre, Tg(Pax6-cre,-GFP)2Pgr
Molecular description: This transgene consists of a minimal promoter, 1.8 kb of murine Pax6 intron 4 encoding a retinal specific regulatory element, a cre recombinase gene, an IRES, a GFP gene, and a polyadenylation signal. Cre and GFP expression are seen in retinal progenitor cells. Line two contains 4 copies of the trandgene inserted into Chr 7 (Chr7: 8525949685287099) to produce a 27 kb deletion.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pax6-cre,GFP)2Pgr activity also observed in:
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Tissue Information
Sensory Organs Other recombinase alleles with activity in Sensory Organs tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 151 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory