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Allele Information
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Allele:
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Shhtm1(EGFP/cre)Cjt
sonic hedgehog;
targeted mutation 1, Clifford J Tabin
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Driver: Shh
Type: Targeted
(Null/knockout, Recombinase)
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Synonym:
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Shh-cre, ShhCreEGFP, Shhcre/Gfp, Shhgfpcre, Shhgfpcre, Shhgfp-Cre, Shh-GFP-Cre, ShhGFP-Cre
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Molecular description:
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A cassette containing an in frame fusion between GFP and cre was inserted at the ATG. Upon recombination, the first 35 base pairs after the ATG were deleted. Fluorescence was detected in the distal posterior region of E10-E12 embryos.
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Shhtm1(EGFP/cre)Cjt activity also observed in:
alimentary system,
branchial arches,
cardiovascular system,
embryo-other,
endocrine system,
head,
hemolymphoid system,
integumental system,
limbs,
mesenchyme,
muscle,
nervous system,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system
(less)
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Tissue Information
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Liver & Biliary System
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Other recombinase alleles with activity in Liver & Biliary System tissues:
Abcg2tm1.1(cre/Esr1*)Jvbe,
Albem1(dre/ERT2)Bzsh,
Albtm1(cre/ERT2)Mtz,
Albtm1(cre/ERT2)Smoc,
Aldh1l1em1(cre/ERT2)Nju,
Alpltm1(cre)Nagy,
Aplnrem3(cre/ERT2)Smoc,
Ccktm1.1(cre)Zjh,
Cd34tm1.1(cre/ERT2)Lizg,
Cd40lgtm1.1(icre)Tega,
Cdh5em1(cre/ERT2)Smoc,
Cdh5em1(nigri)Bzsh,
Cdkn2atm1.1(cre)Dvb,
Cdkn2atm1(cre/ERT2)Mkt,
Cdkn2atm2.1(cre/ERT2)Dvb,
Cldn6tm1(cre/ERT2)Dam,
Clutm2(EGFP/cre/ERT2)Wtsi,
Commd10Tg(Vav1-icre)A2Kio,
Crybb1em1(icre)Cln,
Cx3cr1tm1.1(cre)Jung,
Cx3cr1tm2.1(cre/ERT2)Jung,
Ddx4em1(icre)Jobo,
E2f1Tg(Wnt1-cre)2Sor,
Eportm1.1(EGFP/icre)Uk,
Epxtm1.1(cre)Jlee,
Fgf18tm2.2(cre/ERT2)Dor,
Fgf21em1(cre)Mpot,
Flt4tm2.1(cre/ERT2)Sgo,
Foxa2tm1(cre)Heli,
Foxa2tm2.1(cre/Esr1*)Moon,
Gad2tm2(cre)Zjh,
Gata4tm2(cre/ERT2)Ykaw,
Gfi1tm1(cre)Gan,
Glp1rtm1.1(cre)Cors,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc,
Gt(ROSA)26Sortm1.1(CAG-cre)Jphe,
Gt(ROSA)26Sortm13(dreo)Maoh,
Gt(ROSA)26Sortm14.1(Thy1-dre)Maoh,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Gt(ROSA)26Sortm2(cre/ERT2)Brn,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Gt(ROSA)26Sortm5(dre)Dwi,
Gt(ROSA)26Sortm6(dre/PGR*)Dwi,
Gt(ROSA)26Sortm8(CAG-dre/ERT2)Bzsh,
H2az2Tg(Wnt1-cre)11Rth,
Hlfem1(cre/ERT2)Smoc,
Hlfem2(cre/ERT2)Suda,
Hnf4aem1(dre/ERT2)Bzsh,
Hnf4atm1(cre)Sdv,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Igs2tm1(Cdkn1a-cre/ERT2,-EGFP)Mxu,
Ihhem1(Tomm20/mKate2,dre)Xya,
Il25tm2.1(icre)Lky,
Il25tm3.1(cre/ERT2)Lky,
Krt17tm1(cre)Murr,
Krt19tm1(cre/ERT)Ggu,
Lect2em1(cre)Smoc,
Leprtm2(cre)Rck,
Ltftm1(icre)Tdku,
Ly6atm2.1(cre/Esr1*)Jmol,
Lyve1tm1.1(EGFP/cre)Cys,
Lyz2tm1(cre)Ifo,
Mecomem1(cre/ERT2)Suda,
Mecomtm4.1(cre/ERT2)Aspe,
Mfsd2aem1(cre/ERT2)Bzsh,
Mfsd2aem2(cre/ERT2)Bzsh,
Myf5tm3(cre)Sor,
Myh6em2(cre)Smoc,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx2-5tm2(cre)Rph,
Osr2tm2(cre)Jian,
P2ry12em1(icre/ERT2)Tda,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Pdx1tm1.1(flpo)Most,
Piezo1em2(cre/ERT2)Smoc,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Pms2tm2(cre)Lisk,
Prlrtm1.1(cre)Uboe,
Ptf1atm1.1(cre)Cvw,
Rbpmsem1(cre/ERT2)Yzhe,
Runx1tm1(cre/Esr1*)Ims,
Sox17tm1(icre)Heli,
Sox17tm2.1(icre)Heli,
Sox17tm4.1(icre/ERT2)Heli,
Sox2tm1.1(cre/ERT2)Ykaw,
Speer6-ps1Tg(Alb-cre)21Mgn,
Spink1tm3(cre)Kymm,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Taglntm2(cre)Yec,
Tbx21tm1.1(cre/ERT2)Ayr,
Tbx3em1(cre/ERT2)Toyo,
Tekem1(dre)Bzsh,
Tektm1.1(icre/Esr1*)Hrr,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(ACTA1-cre)79Jme,
Tg(ACTB-cre)1Tes,
Tg(Acvrl1-cre)B1Spo,
Tg(Alb1-cre)1Dlr,
Tg(Alb1-cre)7Gsc,
Tg(Alb-cre/ERT2)#Nor,
Tg(Aldh1l1-cre/ERT2)02Kan,
Tg(Amy2-cre)1Herr,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Car1-cre)5Flt,
Tg(Ccr2-cre/ERT2)12Kuan,
Tg(CD2-icre)4Kio,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)1Nmoc,
Tg(Cdh5-cre)1Spe,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Chst4-cre)1Hkwa,
Tg(Clec4g-icre)1.1Sgoe,
Tg(CMV-cre)1Cgn,
Tg(Col1a2-cre)23Angl,
Tg(Csf1r-cre/Esr1*)1Jwp,
Tg(Csf1r-icre)1Jwp,
Tg(Ctgf-cre)2Aibs,
Tg(Ctsk-cre)8Rda,
Tg(Cyp17a1-icre)AJako,
Tg(Cyp19a1-cre)5909Gle,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp1a1-cre/ERT)1Dwi,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Epo-cre)44Mym,
Tg(Etv2-cre)15508Djg,
Tg(Fabp1-cre)1Jig,
Tg(Fabp4-cre)1Rev,
Tg(Fgfr3-icre/ERT2)4-2Wdr,
Tg(Foxl1-cre)1Khk,
Tg(Gata1-cre)1Sho,
Tg(GATA5-cre)1Krc,
Tg(GFAP-cre)25Mes,
Tg(Glp1r-icre)#Fmgb,
Tg(Grik4-cre)G32-4Stl,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hspa2-cre)1Eddy,
Tg(Il7-cre)CRche,
Tg(Ins2-cre)25Mgn,
Tg(Islr-cre/ERT2)#Tobe,
Tg(Itga2b-cre)AParl,
Tg(Itga2b-cre)NE1/21Emam,
Tg(Itgax-cre)1-1Reiz,
Tg(Kap-icre)29066/2Sig,
Tg(Kdr-cre)15962Brei,
Tg(KRT14-cre)1Amc,
Tg(KRT18-cre/ERT2)1Rgo,
Tg(Krt19-icre)2Hirt,
Tg(Krt8-cre/ERT2,-GFP)1Xin,
Tg(Lck-icre)3779Nik,
Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho,
Tg(Lrat-cre)1Rshw,
Tg(Mafg-Nrf2/cre,-EGFP)737Hozu,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Mx1-cre)29-4Her,
Tg(MYOD1-cre)M23Glh,
Tg(Ncr1-cre/ERT2)#Lll,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Nkx2-5-cre)9Eno,
Tg(Nrp2-cre,-EGFP)#Qsch,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Pf4-icre)Q3Rsko,
Tg(Prdm1-cre)1Masu,
Tg(Prox1-cre/ERT2)1Tmak,
Tg(Prrx1-cre)1Cjt,
Tg(REN-cre)1Haca,
Tg(Retnla-cre)#Voeh,
Tg(Runx1/Hspa1a-cre/ERT2)#Itoy,
Tg(S100a4-cre)1Egn,
Tg(SERPINA1-cre)1Arge,
Tg(SERPINA1-cre/ERT)1Ipc,
Tg(Sim1-cre)1Lowl,
Tg(Spp1-icre/ERT2)#Lecl,
Tg(Stab2-icre)1.2Cger,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jjl,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre)1Ywa,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Arnd,
Tg(Tek-icre/ERT2)1Soff,
Tg(tetO-cre)LC1Bjd,
Tg(Thy1-cre)1Vln,
Tg(Thy1-cre)703Vaw,
Tg(Tie1-cre)9Ref,
Tg(Tshb-cre)4Sac,
Tg(Ttr-cre/Esr1*)1Vco,
Tg(VAV1-cre)1Graf,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Zp3-cre)3Mrt,
Tlr2tm1(cre)Dfil,
Tmprss2tm1.1(cre/ERT2)Ychen,
Tnfrsf19tm1.1(cre/ERT2)Cle,
Trem2em1(cre)Jddl,
Twist2tm1.1(cre)Dor,
Vil1em1(flpo)Lbrl,
Wt1tm1(EGFP/cre)Wtp
(less)
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Recombinase Activity
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References
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Analysis Tools