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Allele Information
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Allele:
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Shhtm2(cre/ERT2)Cjt
sonic hedgehog;
targeted mutation 2, Clifford J Tabin
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Driver: Shh
Type: Targeted
(Inducible, Recombinase)
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Inducer:
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tamoxifen
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Synonym:
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Shh-cre, ShhCreER, ShhCreER, ShhcreERT2, ShhcreERT2, ShhCreERT2, ShhCreesr, Shhtm2(cre-ERT2)Cjt, Shhtm2(cre/ESR1)Cjt
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Molecular description:
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A cassette containing CreERT2 was inserted at the ATG. Upon recombination, the first 35 base pairs after the ATG were deleted. Cre was produced in all cells in which the endogenous mRNA was normally expressed.
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Shhtm2(cre/ERT2)Cjt activity also observed in:
alimentary system,
endocrine system,
extraembryonic component,
head,
limbs
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Tissue Information
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Integumental System
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Other recombinase alleles with activity in Integumental System tissues:
Agrptm1(cre)Lowl,
Airetm3(cre)Mmat,
Alpltm1(cre)Nagy,
Atoh8tm1(EGFP/cre)Gasa,
Axin2tm1(cre/ERT2)Rnu,
Bcl11atm1.1(cre/ERT2)Khal,
Cacna1htm2.1(cre)Glwn,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cdkn2atm1(cre/ERT2)Mkt,
Chattm2(cre)Lowl,
Cldn6tm1(cre/ERT2)Dam,
Clec9atm2.1(icre)Crs,
Clutm2(EGFP/cre/ERT2)Wtsi,
Commd10Tg(Vav1-icre)A2Kio,
Corintm2(cre)Bamo,
Crhtm1(cre)Zjh,
Cx3cr1tm2.1(cre/ERT2)Litt,
Dctem1(cre/ERT2)Enis,
Dcttm1(cre)Bee,
Dkk1tm1(cre/ERT2)Pmy,
Dpttm1.1(cre/ERT2)Snjt,
E2f1Tg(Wnt1-cre)2Sor,
Emx1tm1(cre)Krj,
En1tm2(cre)Wrst,
Epxtm1.1(cre)Jlee,
Foxd1tm1(GFP/cre)Amc,
Gad2tm2(cre)Zjh,
Gfi1tm1(cre)Gan,
Ghem1(cre)Jmz,
Giprem1(icre)Reim,
Gli1tm3(cre/ERT2)Alj,
Glp1rtm1.1(cre)Cors,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc,
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Gt(ROSA)26Sortm2(cre/ERT2)Brn,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Gt(ROSA)26Sortm5(dre)Dwi,
Gt(ROSA)26Sortm6(dre/PGR*)Dwi,
Gt(ROSA)26Sortm8(CAG-dre/ERT2)Bzsh,
H2az2Tg(Wnt1-cre)11Rth,
Hoxc8tm2.1(cre)Mrc,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Hsd11b2tm1(cre)Anft,
Ifi208Tg(Cspg4-cre)1Akik,
Ihhem1(Tomm20/mKate2,dre)Xya,
Kittm1.1(cre)Jmol,
Kittm1(cre/ERT2)Bzsh,
Kittm2.1(cre/Esr1*)Jmol,
Krt14tm1.1(cre/ERT2)Hjg,
Krt14tm1.1(cre)Wbm,
Krt14tm1(cre)Wbm,
Krt17tm1(cre)Murr,
Krt6aem1(icre)Vk,
Leprem2(cre/ERT2)Smoc,
Leprtm2(cre)Rck,
Lgr5em1(cre/ERT2)Kba,
Lgr5tm1.1(cre/ERT2)Npa,
Lgr5tm1(cre/ERT2)Cle,
Lgr6tm2.1(cre/ERT2)Cle,
Lrig1tm1.1(cre/ERT2)Rjc,
Lrig1tm1(cre/ERT2)Kjen,
Lrig1tm2.1(icre/ERT2)Mrc,
Ltftm1(icre)Tdku,
Lyve1tm1.1(EGFP/cre)Cys,
Mcm2tm1(cre/ERT2)Scpr,
Megf6em3(cre)Zzhg,
Mnx1tm4(cre)Tmj,
Mrgprdtm1.1(cre/ERT2)Wql,
Myf5tm3(cre)Sor,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx2-5tm2(cre)Rph,
Notch1tm3(cre)Rko,
Oca2tm1(cre/ERT2)Mymi,
Omptm4(cre)Mom,
Opn3em1(cre)Lan,
Opn5em1(cre)Lan,
Osr2tm2(cre)Jian,
Oxtrtm3.1(Oxtr*,cre)Knis,
Pax3tm1.1(cre/ERT2)Lepr,
Pax3tm1(cre)Joe,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Pdgfratm2.2(flpo)Leol,
Pdgfrbtm1.2(flpo)Leol,
Piezo2tm1.1(cre)Apat,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Pmelem1(rtTA,tetO-icre)Osaw,
Prdm1tm3(icre)Rob,
Prdm1tm5.1(cre/ERT2)Rob,
Prlrtm1.1(cre)Uboe,
Procrtm1.1(cre/ERT2)Yaz,
Pvalbtm1(cre)Arbr,
Scn9aem1(icre)Itsu,
Shhtm1(EGFP/cre)Cjt,
Slc17a6tm2(cre)Lowl,
Smoc2tm1(cre/ERT2)Cle,
Sox9em1(cre/ERT2)Tchn,
Ssttm2.1(cre)Zjh,
Taglntm2(cre)Yec,
Tbx3em1(cre/ERT2)Toyo,
Tcf7l1tm1.1(cre/ERT2)Hng,
Tg(ACTA1-cre)1Mll,
Tg(ACTA1-cre)79Jme,
Tg(Actl6b-cre)4092Jiwu,
Tg(Adipoq-cre)1Evdr,
Tg(Aire-cre)410-5Mmat,
Tg(Bmx-cre/ERT2)1Rha,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Camk2a-cre)1Nobs,
Tg(CD2-icre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Cdx2-cre)R337Npln,
Tg(Ckmm-cre)5Khn,
Tg(CMV-cre)1Cgn,
Tg(CMV-cre/ERT)1Ipc,
Tg(Col10a1-cre)1Xya,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a2-cre)23Angl,
Tg(Col1a2-cre/ERT,-ALPP)7Cpd,
Tg(COL2A1-cre)1Wag,
Tg(Col6a1-cre)1Gkl,
Tg(Cryaa-cre)10Mlr,
Tg(Cspg4-cre/Esr1*)BAkik,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp19a1-cre)5909Gle,
Tg(Cyp19a1-cre)5912Gle,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(dlx5a-cre)1Mekk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Elf5-cre/ERT2,-GFP)2Rcha,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Abel,
Tg(Fabp4-cre)1Rev,
Tg(Fabp4-cre/ERT2)1Ipc,
Tgfb3tm1(cre)Vk,
Tg(Flt1-cre/ERT2)1Tmak,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(GH1-cre)1Sac,
Tg(Ghrhr-cre)3242Lsk,
Tg(Grem1-cre/ERT)3Tcw,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxa5-cre)444CLjea,
Tg(Hoxa5-cre)447BLjea,
Tg(Hoxb8-cre)1403Uze,
Tg(hs1163-Ccre,-lacZ)1Fawa,
Tg(Hspa2-cre)1Eddy,
Tg(I12b-cre)1Jlr,
Tg(Il7-cre)CRche,
Tg(Ins2-cre)25Mgn,
Tg(Islr-cre/ERT2)#Tobe,
Tg(Itgax-cre)1-1Reiz,
Tg(Klf4-cre/ERT)1Wai,
Tg(Krt10-cre/ERT)#Efu,
Tg(Krt1-15-cre/PGR*)22Cot,
Tg(KRT14-cre)1Amc,
Tg(KRT14-cre)1Cgn,
Tg(KRT14-cre)1Efu,
Tg(KRT14-cre)1Ipc,
Tg(KRT14-cre)43Smr,
Tg(KRT14-cre)8Brn,
Tg(KRT14-cre/ERT)20Efu,
Tg(KRT14-cre/ERT2)1Ipc,
Tg(KRT14-cre/PGR)1Der,
Tg(Krt1-5-cre/ERT)1Ipc,
Tg(Krt15-cre/ERT2)1Johu,
Tg(KRT18-cre/ERT2)1Rgo,
Tg(Krt2-6a-cre)1Ism,
Tg(KRT5-cre)5132Jlj,
Tg(KRT5-cre/ERT2)2Ipc,
Tg(KRT5-cre/ERT2)#Mym,
Tg(KRT5-cre/ERT)ICmch,
Tg(KRT5-cre/ERT)SCmch,
Tg(KRT5-cre/PGR)1Der,
Tg(Krt8-cre/ERT2,-GFP)1Xin,
Tg(LGB-cre)74Acl,
Tg(LTF-EGFP/cre/PGR)15Klin,
Tg(Lyve1-cre/ERT2)49Rtem,
Tgm3tm2(EGFP/cre/ERT2)Wtsi,
Tg(Mitf-cre)710-59Gsb,
Tg(Mitf-cre)7114Gsb,
Tg(MMTV-cre)105Ayn,
Tg(MMTV-cre)1Mam,
Tg(MMTV-cre)4Mam,
Tg(MMTV-cre)7Mul,
Tg(MMTV-cre)AElee,
Tg(MMTV-cre)BElee,
Tg(MMTV-cre)#Mam,
Tg(MMTV-flpo)11Gcr,
Tg(MMTV-flpo)29542Kuw,
Tg(MMTV-flpo)9Gcr,
Tg(Mpz-cre)94Imeg,
Tg(Mrgprb2-EGFP/cre)2Xzd,
Tg(Mrgprb2-EGFP/cre)3Xzd,
Tg(Mrgprb2-EGFP/cre)#Xzd,
Tg(Msx2-cre/ERT2)1Nono,
Tg(Msx2-cre/ERT2)2Nono,
Tg(Mx1-cre)1Cgn,
Tg(Myh11-cre,-EGFP)2Mik,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Ntrk3-cre/ERT2)#Phep,
Tg(Pax3-cre)1Joe,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Pdpn-cre)HRkl,
Tg(Pdzk1ip1-cre/ERT2)#Reiz,
Tg(Pf4-icre)Q3Rsko,
Tg(Pitx2-cre/Esr1*)#Hmd,
Tg(Plp1-cre/ERT2)1Ueli,
Tg(Plp1-cre/ERT)3Pop,
Tg(Pou3f4-cre)32Cren,
Tg(Prdm1-cre)1Masu,
Tg(Prrx1-cre)1Cjt,
Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka,
Tg(Relb-cre)53Rie,
Tg(Retn-cre)1Laz,
Tg(Retnla-cre)#Voeh,
Tg(Rr437-cre)#Hmd,
Tg(rtetR-tetO-cre)40Mhz,
Tg(S100a4-cre)1Egn,
Tg(S100a4-cre)1Gle,
Tg(S100a4-flpo)3Lba,
Tg(S100b-cre)20Ito,
Tg(Scnn1a-cre)3Aibs,
Tg(Sim1-cre)1Lowl,
Tg(Stab2-icre)1.2Cger,
Tg(Tagln-cre)1Her,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tbx18-icre)3Fech,
Tg(TCF/Lef1-cre/ERT2)#Ypc,
Tg(Tek-cre)1Ywa,
Tg(Tek-icre/ERT2)1Soff,
Tg(Thy1-cre)1Vln,
Tg(Thy1-cre)703Vaw,
Tg(Tie1-cre)9Ref,
Tg(Tyr-cre)1Gfk,
Tg(Tyr-cre)1Lru,
Tg(Tyr-cre)2Lru,
Tg(Tyr-cre)3Gfk,
Tg(Tyr-cre/ERT2)13Bos,
Tg(Tyr-cre/ERT2)1Lru,
Tg(Tyr-cre/ERT,-Hras1*,-Trap1a)10BJvde,
Tg(Tyr-cre)#Lru,
Tg(Ucp1-cre)1Evdr,
Tg(Ucp1-cre)#Brsp,
Tg(Wap-cre)11738Mam,
Tg(Wap-cre)1Gsc,
Tg(Wap-rtTA-cre)10Whl,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt7a-EGFP/cre)#Bhr,
Tg(WT1-cre)1Asc,
Tg(Zp3-cre)3Mrt,
Thtm1(cre)Te,
Tmprss2tm1.1(cre/ERT2)Ychen,
Trpv4em1(cre/ERT2)Amc,
Twist2tm1.1(cre)Dor,
Ucp1em1(cre)Chez,
Vimem1(cre/ERT2)Bzsh,
Wt1tm1(EGFP/cre)Wtp
(less)
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Images
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Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail.
Reset Images
J:253583
Full Image
Fig. Shh E15.5 hair follicle
J:253583
Fig. Shh E15.5vibrisae front
J:253583
Fig. Shh E15.5 vibrisae left
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Recombinase Activity
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Click heading to re-sort table.
Assays
Genotypic Background
Result Notes
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References
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