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Tg(Gdf5-cre,-ALPP)1Kng - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Gdf5-cre,-ALPP)1Kng
transgene insertion 1, David M Kingsley 		Driver: Gdf5
Type: Transgenic (Recombinase)
Synonym: CAG(A), Gdf5-Cre
Molecular description: This transgene contains Cre recombinase and human placental alkaline phosphatase under the control of Gdf5 promoter and enhancer elements. A BAC containing the Gdf5 locus was modified by the insertion of a cre-IRES-ALPP into the translational start site to create the transgene. Gdf5 drives expression in developing joints. This line represents three that were created.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Gdf5-cre,-ALPP)1Kng activity also observed in:
limbs, mesenchyme, mouse-other
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Images
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J:243210 Fig. 4 J:293210 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 23 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory