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Tg(Tek-cre)1Rwng - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tek-cre)1Rwng
transgene insertion 1, Rong Wang 		Driver: Tek
Type: Transgenic (Recombinase)
Synonym: Tg(Tek-cre)1Lfr, tie2-cre, Tie2Cre
Molecular description: The endothelial specific receptor tyrosine kinase promoter was used to drive expression of cre recombinase. Nine founder lines were produced and one of these was selected for use that efficiently mediated gene excision. Cre was active in the blood islands of extraembryonic mesoderm at E7.5 and in the dorsal aortae at E8.5. By E11.5 it was active in the endothelial cells of all blood vessels.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tek-cre)1Rwng activity also observed in:
embryo-other, head, nervous system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:102190 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 12 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory