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Isl1tm1(cre)Sev - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Isl1tm1(cre)Sev
ISL1 transcription factor, LIM/homeodomain; targeted mutation 1, Sylvia Evans 		Driver: Isl1
Type: Targeted (Recombinase)
Synonym: Isl1:Cre, Isl1Cre, Isl1Cre
Molecular description: A cre gene and frt-flanked neo cassette were inserted 6 bp upstream of the translation initiation codon. The neo cassette was removed by germ line, flp-mediated recombination. Expression of cre is regulated by the endogenous promoter.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Isl1tm1(cre)Sev activity also observed in:
muscle
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:220957 Fig. 8
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 105 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory