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Tg(Mef2c-cre)2Blk - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Mef2c-cre)2Blk
transgene insertion 2, Brian L Black 		Driver: Mef2c
Type: Transgenic (Recombinase)
Synonym: AHF-Cre, Mef2c-AHFCre, mef2c-AHF-Cre line 200A
Molecular description: The Mef2c anterior heart field enhancer and promoter (AHF) was cloned into a cre expression plasmid with the cre cDNA and the SV40 splice sequence and the polyA signal sequence. The Mef2c-AHF-Cre fragment was injected into male pronuclei of fertilized oocytes. Three founder lines were initially characterized and line 200A was used for further analysis.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Mef2c-cre)2Blk activity also observed in:
branchial arches, muscle, respiratory system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:103545 Fig. 3 J:103545 Fig. 4 J:103545 Fig. 5 J:103545 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 86 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory