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Tg(Pomc1-cre)16Lowl - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pomc1-cre)16Lowl
transgene insertion 16, Bradford B Lowell 		Driver: Pomc
Type: Transgenic (Recombinase)
Synonym: Pomc-Cre, Pomc-Cre(BAC1), Tg(Pomc1-cre)1Lowl
Molecular description: This transgene consists of a Pomc1 BAC such that cre is driven by Pomc1 regulatory elements. Cre is expressed in POMC neurons in the arcuate nucleus of the hypothalamus and scattered cre activity is also seen in the dentate gyrus of the hippocampus.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pomc1-cre)16Lowl activity also observed in:
head, nervous system, renal & urinary system, reproductive system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Images
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J:184578 Full Image
Fig. Pomc Embryo 1 E15.5 J:184578 Full Image
Fig. Pomc Embryo 2 E15.5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 159 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory