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Tg(Nes-cre/ERT2)5-1Imayo - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nes-cre/ERT2)5-1Imayo
transgene insertion 5-1, Itaru Imayoshi 		Driver: Nes
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Nes-CreERT2, Nestin-CreER.line5, Tg(Nes-cre/ERT2)5-1Kag
Molecular description: This transgene consists of a 5.8 kb fragment of the rat Nes promoter and a 1.8 kb fragment of the second intron of Nes driving expression of a tamoxifen-inducible form of cre recombinase followed by an SV40 poly A sequence. This line show tamoxifen-inducible Cre activity in the developing nervous system and no Cre activity in the absence of tamoxifen.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nes-cre/ERT2)5-1Imayo activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:110145 Fig. 2 J:110145 Fig. 4 J:110145 Fig. 5 J:110145 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 25 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory