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Allele Information
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Allele:
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Tg(TPO-cre)1Shk
transgene insertion 1, Shioko Kimura
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Driver: TPO
Type: Transgenic
(Recombinase)
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Synonym:
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TPO-cre
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Molecular description:
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This transgene expresses cre recombinase under the control of the human thyroid peroxidase gene promoter. Insulator sequences were placed upstream and downstream of the TPO-cre cassette. The insertion site was found to be between bp 12,372,316 and 12,372,324 on mouse chromosome 9, near Cntn5 and Jrkl, approximately 1.5 and 0.9 Mbp from the transgene, respectively (J:303278).
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(TPO-cre)1Shk activity also observed in:
alimentary system,
renal & urinary system
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Tissue Information
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Endocrine System
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Other recombinase alleles with activity in Endocrine System tissues:
7630403G23RikTg(Th-cre)1Tmd,
Agrptm1(cre)Lowl,
Alpltm1(cre)Nagy,
Ccktm1.1(cre)Zjh,
Cfap126tm1.1(icre)Heli,
Commd10Tg(Vav1-icre)A2Kio,
Cpa1tm1(cre/ERT2)Dam,
Crhtm1.1(flpo)Bsab,
Crhtm1(cre)Zjh,
Cx3cr1tm1.1(cre)Jung,
Cx3cr1tm2.1(cre/ERT2)Jung,
Cyp11a1tm1(GFP/cre)Pzg,
E2f1Tg(Wnt1-cre)2Sor,
Fgf16tm1.1(cre)Sms,
Foxd1tm1(GFP/cre)Amc,
Foxl2tm1(GFP/cre/ERT2)Pzg,
Gad2tm2(cre)Zjh,
Gcgem1(cre)Utr,
Gcgtm1.1(cre/ERT2)Yasu,
Ghem1(cre)Jmz,
Ghsrtm1.1(cre)Jmz,
Glp1rtm1.1(cre)Cors,
Gnao1tm2(EGFP/cre/ERT2)Wtsi,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gper1em1(cre)Smoc,
Gt(ROSA)26Sortm1.1(CAG-cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
H2az2Tg(Wnt1-cre)11Rth,
Hand2em1(dre)Pjen,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm1(TG-cre)1Sasr,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Ifi208Tg(Cspg4-cre)1Akik,
Ihhem1(Tomm20/mKate2,dre)Xya,
Ins1tm1.1(cre)Thor,
Ins1tm2.1(cre/ERT2)Thor,
Krt17tm1(cre)Murr,
Krt19tm1(cre/ERT)Ggu,
Leprtm2(cre)Rck,
Lyve1tm1.1(EGFP/cre)Cys,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx2-1tm1.1(cre/ERT2)Zjh,
Nkx2-2tm4.1(cre/EGFP)Suss,
Nkx2-5tm2(cre)Rph,
Notch1tm3(cre)Rko,
Npvftm1.1(icre)Gand,
Nxph4em1(cre)Zak,
Omptm4(cre)Mom,
Oprk1tm1.1(cre)Sros,
Osr2tm2(cre)Jian,
Oxttm1.1(icre)Ksak,
Pax3tm1(cre)Joe,
Pax7tm2.1(cre/ERT2)Fan,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdx1tm1.1(dre)Gkg,
Pdyntm1.1(cre)Mjkr,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Prlrtm1.1(cre)Uboe,
Ptf1atm1.1(cre)Cvw,
Ptf1atm1(flpo)Hcrd,
Raxtm1.1(cre/ERT2)Sbls,
Rxfp1em1(cre)Ngai,
Setd4em1(cre)Wjy,
Setd4tm2.1(cre/ERT2)Wjy,
Sfta3tm1.1(cre/ERT2)Eem,
Shhtm1(EGFP/cre)Cjt,
Shhtm2(cre/ERT2)Cjt,
Slc17a6tm2(cre)Lowl,
Slc26a9em1(cre)Sms,
Sox2tm1.1(cre/ERT2)Jpmb,
Spink1tm3(cre)Kymm,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Ssttm2.1(cre)Zjh,
Taglntm2(cre)Yec,
Tbx3em1(cre)Mhts,
Tg(ACTA1-cre)79Jme,
Tg(ACTB-cre)1Tes,
Tg(ACTFLPe)9205Dym,
Tg(Actl6b-cre)4092Jiwu,
Tg(Adipoq-cre)1Evdr,
Tg(Akr1b7-cre)1Anm,
Tg(Alb1-cre)1Dlr,
Tg(Amh-cre)8815Reb,
Tg(Amy2-cre)1Herr,
Tg(CA2-cre)1Subw,
Tg(CA2-cre/Esr1*)1Subw,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Camk2a-cre)1Nobs,
Tg(Camk2a-cre/ERT2)1Aibs,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)7Mlia,
Tg(CDX2-cre)101Erf,
Tg(Cga-cre)3Sac,
Tg(Cga-icre)961Sac,
Tg(CMV-cre)1Cgn,
Tg(Crx-cre)1Tfur,
Tg(Cryaa-cre)10Mlr,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp11a1-cre)16Mchu,
Tg(Cyp17a1-icre)AJako,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp39a1-cre)1Aibs,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Dbh-cre/ERT2)198.1Hroh,
Tg(Ddx4-cre)1Dcas,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Rev,
Tg(Fev-cre)FF9Pasq,
Tg(Gcg-cre)1Herr,
Tg(Gcg-cre)1Slib,
Tg(Gcg-icre)23Cshi,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(Gfap-cre)77.6Mvs,
Tg(GH1-cre)1Sac,
Tg(Gh1-cre)bKnmn,
Tg(Ghrhr-cre)3242Lsk,
Tg(Ghrl-cre)E7Jmz,
Tg(Ghrl-icre)#Weiz,
Tg(Glp1r-icre)#Fmgb,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Inha-cre)1Zuk,
Tg(Inha-cre)2Zuk,
Tg(Inha-cre)3Zuk,
Tg(Ins1-cre)25Utr,
Tg(Ins1-cre,-DsRed*T3)#Caoy,
Tg(Ins1-cre/ERT)1Lphi,
Tg(Ins1-cre/ERT2)#Pesch,
Tg(Ins2-cre)23Herr,
Tg(Ins2-cre)25Mgn,
Tg(Ins2-cre/ERT)1Dam,
Tg(Ins2-tTA,tetO-cre)1Ctlh,
Tg(INS-icre)18Msdr,
Tg(Itgax-cre)1-1Reiz,
Tg(Lck-icre)3779Nik,
Tg(Lhb-cre)1Sac,
Tg(LHX3-cre)#Sjr,
Tg(Mbp-cre)6Gvn,
Tg(Mbp-cre)9Gvn,
Tg(Mchr1-cre/ERT2)3Nbe,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Nes-cre)1Kln,
Tg(Neurod1-cre)1Able,
Tg(Neurog3-cre)1Dam,
Tg(NEUROG3-cre)1Herr,
Tg(Neurog3-cre)C1Able,
Tg(Neurog3-cre/ERT2)1Able,
Tg(Neurog3-cre/Esr1*)1Dam,
Tg(Nkx2-1-cre)2Sand,
Tg(NPHS2-cre)295Lbh,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Nr5a1-cre)7Lowl,
Tg(Nr5a1-cre/ERT2)4Kmor,
Tg(Pax4-cre)1Dam,
Tg(Pax6-cre)1Rilm,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pcp2-cre)2Mpin,
Tg(Pdx1-cre)1Herr,
Tg(Pdx1-cre)6Cvw,
Tg(Pdx1-cre)89.1Dam,
Tg(Pdx1-cre/Esr1*)1Mga,
Tg(Pdx1-cre/Esr1*)35.10Dam,
Tg(Pdx1-cre/Esr1*)35.6Dam,
Tg(Pdx1-cre/Esr1*)#Dam,
Tg(Pf4-icre)Q3Rsko,
Tg(Pitx1-cre)7Rsd,
Tg(Pomc1-cre)16Lowl,
Tg(Pomc-cre)5Brn,
Tg(Pomc*-cre/ERT2)#Rlb,
Tg(Pomc*-cre)#Jdr,
Tg(Pomc-dre)#Jcbr,
Tg(Prdm1-cre)1Masu,
Tg(Prl-cre)#Salr,
Tg(Prm-cre)58Og,
Tg(Prop1-cre)1Rsd,
Tg(Prop1-icre)517Sac,
Tg(Prrx1-cre)1Cjt,
Tg(PTH-cre)4167Slib,
Tg(Rarb-cre)1Bhr,
Tg(Relb-cre)53Rie,
Tg(REN-cre)1Haca,
Tg(Ren-cre)#Kwg,
Tg(Scnn1a-cre)3Aibs,
Tg(Sim1-cre)1Lowl,
Tg(Stra8-icre)1Reb,
Tg(Sycp1-cre)4Min,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)1Ywa,
Tg(tetO-cre)1Jaw,
Tg(Tg-cre)1Soff,
Tg(Tg-cre/ERT2)1Kero,
Tg(Th-cre)12Mrub,
Tg(Thy1-cre)1Vln,
Tg(Tshb-cre)4Sac,
Tg(Tyr-cre)1Gfk,
Tg(Tyr-cre/ERT2)13Bos,
Tg(Ucp1-cre)1Evdr,
Tg(Vav1-cre)8Cgp,
Tg(Vil1-cre)997Gum,
Tg(Wfs1-cre/ERT2)3Aibs,
Thtm1(cre)Te,
Tmprss2tm1.1(cre/ERT2)Ychen,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh,
Wt1tm1(EGFP/cre)Wtp
(less)
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Images
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J:92293
Fig. 3
J:92293
Fig. 4
J:92293
Fig. 5
J:92293
Fig. 6
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Recombinase Activity
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Assays
Genotypic Background
Result Notes
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References
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