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Tg(GFAP-cre)1Kdmc - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(GFAP-cre)1Kdmc
transgene insertion 1, Ken D McCarthy 		Driver: GFAP
Type: Transgenic (Recombinase)
Synonym: GFAP-cre
Molecular description: A human GFAP promoter was used to drive expression of Cre recombinase, with an intron and polyadenylation signals from the mouse protamine-1 gene. The promoter-cre fragment was surrounded by four copies of a genomic insulator. Cre recombinase expression is restricted to GFAP-positive astrocytes in brain; neurons and oligodendrocytes do not express the Cre protein.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(GFAP-cre)1Kdmc activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 25 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory