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Tg(CDX2-cre)101Erf - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Tg(CDX2-cre)101Erf
transgene insertion 101, Eric R Fearon 		Driver: CDX2
Type: Transgenic (Recombinase)
Synonym: CDX2P 9.5-NLS Cre, CDX2P9.5-NLSCre, CDX2P-NLS Cre, CPC, Tg(CDX2-cre)1Erf
Molecular description: The CDX2P9.5-NLSCre transgene was designed with a 9.5 kb promoter fragment from the 5' flanking sequences of human caudal type homeo box 2 (CDX2) gene, a Cre recombinase gene with nuclear localization signal, and a bovine growth hormone polyadenylation cassette. This transgene was injected into (C57BL/6J x SJL/J) hybrid cells. Transgenic founders (line 101) were found to have approximately 50 copies of the transgene and were bred to C57BL/6J mice. Cre expression is noted in epithelium of the ileum and cecum and throughout the colon. During early development, expression is observed throughout the caudal region of the embryo.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(CDX2-cre)101Erf activity also observed in:
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Images
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J:216865 Full Image
Fig. CDX2 E10.5 Hindlimb bud J:216865 Full Image
Fig. CDX2 E15.5 Arm
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 44 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory