|
|
|
Allele Information
|
|
Allele:
|
Tg(CDX2-cre)101Erf
transgene insertion 101, Eric R Fearon
|
Driver: CDX2
Type: Transgenic
(Recombinase)
|
|
|
Synonym:
|
CDX2P 9.5-NLS Cre, CDX2P9.5-NLSCre, CDX2P-NLS Cre, CPC, Tg(CDX2-cre)1Erf
|
|
Molecular description:
|
The CDX2P9.5-NLSCre transgene was designed with a 9.5 kb promoter fragment from the 5' flanking sequences of human caudal type homeo box 2 (CDX2) gene, a Cre recombinase gene with nuclear localization signal, and a bovine growth hormone polyadenylation cassette. This transgene was injected into (C57BL/6J x SJL/J) hybrid cells. Transgenic founders (line 101) were found to have approximately 50 copies of the transgene and were bred to C57BL/6J mice. Cre expression is noted in epithelium of the ileum and cecum and throughout the colon. During early development, expression is observed throughout the caudal region of the embryo.
|
|
Find mice (IMSR):
|
Mouse Strains:
1
strain available
Cell Lines:
0 lines available
|
|
Additional Tissues:
|
Tg(CDX2-cre)101Erf activity also observed in:
adipose tissue,
alimentary system,
cardiovascular system,
cavities & their linings,
embryo-other,
endocrine system,
head,
hemolymphoid system,
integumental system,
limbs,
liver & biliary system,
mesenchyme,
mouse-other,
muscle,
nervous system,
renal & urinary system,
reproductive system,
respiratory system,
skeletal system
(less)
|
|
|
Tissue Information
|
|
Tail
|
Other recombinase alleles with activity in Tail tissues:
Alpltm1(cre)Nagy,
Calb2tm1(cre)Zjh,
E2f1Tg(Wnt1-cre)2Sor,
En1tm2(cre)Wrst,
Etv5tm1(cre/ERT2)Brst,
Fgf18tm2.2(cre/ERT2)Dor,
Foxd1tm1(GFP/cre)Amc,
H2az2Tg(Wnt1-cre)11Rth,
Hoxa13tm1.1(cre)Mlkn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Myf5tm3(cre)Sor,
Nkx1-2tm2296.1(cre/ERT2)Arte,
Omptm4(cre)Mom,
Osr2tm2(cre)Jian,
Pax3tm1.1(cre/ERT2)Lepr,
Pax3tm1(cre)Joe,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Sall4tm1.1(EGFP/cre/ERT2)Ykawa,
Scxtm1.1(cre)Shuk,
Six1tm1(cre)Xli,
Slc17a6tm2(cre)Lowl,
Taglntm2(cre)Yec,
Tg(Acan-cre/ERT2,-luc)1Gbg,
Tg(ACTA1-cre)79Jme,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Cdh5-cre)7Mlia,
Tg(CDX2-cre*)189Erf,
Tg(Cdx2-cre)R337Npln,
Tg(Cga-cre)3Sac,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Col2a1-rtTA,tetO-cre)22Pjro,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(Dll1-cre)33Dchp,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Rev,
Tgfb3tm1(cre)Vk,
Tg(Foxa2/Sox9-cre,-lacZ)#Vleu,
Tg(Foxa3-cre)1Khk,
Tg(GDF6-cre/ERT2)L2Kng,
Tg(GFAP-cre)25Mes,
Tg(Hhex-cre,-GFP)1Ksz,
Tg(Hoxb3-cre)1Pkht,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Ins2-cre)25Mgn,
Tg(Mef2c-cre)1Blk,
Tg(Mitf-cre)710-59Gsb,
Tg(Mitf-cre)7114Gsb,
Tg(Nodal*-cre)#Mku,
Tg(Pax3-cre)1Joe,
Tg(Pcp2-cre)1Amc,
Tg(Pitx3-cre/ERT2)1Yqd,
Tg(Prdm1-cre)1Masu,
Tg(Prph1-cre)35Dmd,
Tg(Sim1-cre)1Lowl,
Tg(Sox10-ERT2/cre/ERT2)17Sor,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jomm,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tbx6-cre)#Rsam,
Tg(Thy1-cre)1Vln,
Tg(Tie1-cre)9Ref,
Tg(Ure2-cre)1Jlr,
Tg(Zp3-cre)3Mrt,
Twist2tm1.1(cre)Dor,
Wt1tm1(EGFP/cre)Wtp
(less)
|
|
|
Images
|
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail.
Reset Images
J:216865
Full Image
Fig. CDX2 E15.5 Vertebra Caudal
|
|
Recombinase Activity
|
Click heading to re-sort table.
|
|
References
|
|
Analysis Tools