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Tg(Aqp2-cre)1Dek - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Aqp2-cre)1Dek
transgene insertion 1, Donald E Kohan 		Driver: Aqp2
Type: Transgenic (Recombinase)
Synonym: AQP2-Cre
Molecular description: This transgene contains a 9.5 kb fragment of the mouse aquaporin 2 gene 5'-flanking region placed upstream of a Cre recombinase sequence (with SV40 nuclear localization signal at the amino terminus and an 11-amino acid epitope tag derived from Herpes simplex virus glycoprotein D located at the carboxy terminus). The aquaporin regulatory sequences drive Cre expression in the collecting ducts of the kidney and in sperm.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Aqp2-cre)1Dek activity also observed in:
head, nervous system, reproductive system
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Images
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J:193672 Full Image
Fig. Aqp2 Kidney P56 J:99873 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 33 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory