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Allele Information
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Allele:
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Tbx1tm6(cre)Bld
T-box 1;
targeted mutation 6, Antonio Baldini
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Driver: Tbx1
Type: Targeted
(Recombinase)
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Synonym:
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Tbx1Cre
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Molecular description:
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An IRES-cre cassette was inserted into exon 5. Expression of cre is induced in head mesoderm and mesoderm located dorsally to the cardiac cresent at E75. to E8.5, most mesoderm dorsal and lateral to the pharynx and head mesoderm at 4- and 6-somite stage, and mesoderm that virtually surrounds the pharynx at 8-somite stage in a pattern that is similar to Tbx1 expression. Author states that this is a null allele.
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Tbx1tm6(cre)Bld activity also observed in:
cardiovascular system
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Tissue Information
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Muscle
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Other recombinase alleles with activity in Muscle tissues:
A1cfTg(Myh6-cre/Esr1*)1Jmk,
Abcg2tm1.1(cre/Esr1*)Jvbe,
Acantm1(cre/ERT2)Crm,
Aldh1l1em1(cre/ERT2)Nju,
Alpltm1(cre)Nagy,
Aplntm1.1(cre/ERT2)Bzsh,
Atoh8tm1(EGFP/cre)Gasa,
Cacna1htm2.1(cre)Glwn,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cdh5em1(cre/ERT2)Smoc,
Chattm2(cre)Lowl,
Clutm2(EGFP/cre/ERT2)Wtsi,
Commd10Tg(Vav1-icre)A2Kio,
Dmp1tm1(cre)Msue,
E2f1Tg(Wnt1-cre)2Sor,
Emx1tm1(cre)Krj,
En1tm2(cre)Wrst,
Etv1tm1.1(cre/ERT2)Zjh,
Foxa2tm2.1(cre/Esr1*)Moon,
Foxd1tm1(GFP/cre)Amc,
Gad2tm2(cre)Zjh,
Gjd3tm1.1(cre/EGFP)Nmun,
Gli1tm3(cre/ERT2)Alj,
Gnao1tm2(EGFP/cre/ERT2)Wtsi,
Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(FLP1)Dym,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Gt(ROSA)26Sortm8(CAG-dre/ERT2)Bzsh,
H2az2Tg(Wnt1-cre)11Rth,
Hand1tm1.1(EGFP/cre)Abfi,
Hcn4tm1(cre/ERT2)Anlu,
HhatTg(TFAP2A-cre)1Will,
Hic1tm2.1(cre/ERT2)Tmun,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Hsd11b2tm1(cre)Anft,
Ifi208Tg(Cspg4-cre)1Akik,
Igs2tm1(Cdkn1a-cre/ERT2,-EGFP)Mxu,
Igs2tm2(Smarcd3-cre/ERT2)Bbr,
Isl1tm1(cre/Esr1*)Krc,
Isl1tm1(cre)Sev,
Isl1tm1(cre)Tmj,
Kdrtm1(cre)Sato,
Kittm1.1(cre)Jmol,
Krt17tm1(cre)Murr,
Leprtm2(cre)Rck,
Lyve1tm1.1(EGFP/cre)Cys,
Lyz2tm1(cre)Ifo,
Mgptm1.1(cre)Borr,
Mnx1tm4(cre)Tmj,
Myf5tm1.1(cre/Esr1*)Trdo,
Myf5tm1.1(cre)Mrc,
Myf5tm1(cre/Esr1*)Trdo,
Myf5tm1(cre)Mrc,
Myf5tm3(cre)Sor,
Myf6tm1.1(cre/ERT2)Lepr,
Myf6tm1.1(cre/Esr1*)Cklr,
Myf6tm1(cre)Mrc,
Myf6tm2(cre)Mrc,
Myh6em2(cre)Smoc,
Myl1tm1.1(cre/ERT2)Lepr,
Myl2tm1(cre)Krc,
Myocdtm1(cre)Dzw,
Myocdtm1(cre)Jomm,
Myod1tm1.1(cre/ERT2)Lepr,
Myod1tm2.1(icre)Glh,
Myogtm1.1(cre/ERT2)Lepr,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nfatc1em4(cre/ERT2)Bzsh,
Nfatc1tm1.1(cre/ERT2)Bzsh,
Nkx2-5tm1(cre)Rjs,
Nkx2-5tm2(cre)Rph,
Nos1tm1.1(cre/ERT2)Zjh,
Notch1tm3(cre)Rko,
Omptm4(cre)Mom,
Oprk1tm1.1(cre)Sros,
Osr2tm2(cre)Jian,
P2rx2tm1.1(cre)Ttc,
Pax3tm1.1(cre/ERT2)Lepr,
Pax3tm1(cre)Joe,
Pax7tm1(cre/ERT2)Gaka,
Pax7tm1(cre/Esr1*)Cklr,
Pax7tm1(cre)Mrc,
Pax7tm2.1(cre/ERT2)Fan,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(cre/ERT2)Trdo,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Pdgfrbtm1.1(cre/ERT2)Csln,
Pitx2tm4(cre)Jfm,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Pms2tm2(cre)Lisk,
Pvalbtm1(cre)Arbr,
Runx3tm1(flpo)Noo,
Scxtm1.1(cre)Shuk,
Sema3atm1.1(cre/ERT2)Bzsh,
Shhtm1(EGFP/cre)Cjt,
Shroom3Gt(ROSA53)Sor,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Ssttm2.1(cre)Zjh,
Taglntm1(cre/ERT2)Feil,
Taglntm2(cre)Yec,
Tcf7l2tm3.1(cre/ERT2)Mrc,
Tg(ACTA1-cre)1Mll,
Tg(ACTA1-cre)79Jme,
Tg(ACTA1-cre/ERT2)97.16Mtz,
Tg(ACTA1-cre/Esr1*)2Kesr,
Tg(ACTA1-rtTA,tetO-cre)102Monk,
Tg(Acta2-cre/ERT2)12Pcn,
Tg(Acta2-cre/ERT2)1Ikal,
Tg(Acta2-cre/ERT2)51Pcn,
Tg(ACTC1-cre)1Miwa,
Tg(Alb1-cre)1Dlr,
Tg(Bmx-cre/ERT2)1Rha,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Camk2a-cre/ERT2)1Aibs,
Tg(CD2-icre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Cga-cre)3Sac,
Tg(Ckmm-cre)5Khn,
Tg(CMV-cre)1And,
Tg(CMV-cre)1Cgn,
Tg(COL2A1-cre)1Wag,
Tg(Col6a1-cre)1Gkl,
Tg(Colq-cre)#Kohno,
Tg(Csf1r-icre)1Jwp,
Tg(Cspg4-cre/Esr1*)BAkik,
Tg(Csrp1-cre)1Sjc,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp39a1-cre)1Aibs,
Tg(Dct-cre)1Apdn,
Tg(Ddx4-cre)1Dcas,
Tg(dlx5a-cre)1Mekk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Abel,
Tg(Fabp4-cre)1Rev,
Tg(Fabp4-cre/ERT2)1Ipc,
Tg(Fgfr3-icre/ERT2)4-2Wdr,
Tg(Gabra6-cre)B1Lfr,
Tg(Gata1-cre)1Sho,
Tg(GATA5-cre)1Krc,
Tg(GATA6-cre)#Jbeb,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(Gfap-cre)77.6Mvs,
Tg(Gjb6-cre/ERT2)53-33Fwp,
Tg(Glp1r-icre)#Fmgb,
Tg(Grik4-cre)G32-4Stl,
Tg(Hand1-EGFP/cre)#Abfi,
Tg(Hoxb8-cre)1403Uze,
Tg(Hspa2-cre)1Eddy,
Tg(Ins2-cre)25Mgn,
Tg(Islr-cre/ERT2)#Tobe,
Tg(Itgax-cre)1-1Reiz,
Tg(Kcne1-cre/ERT2)1Imos,
Tg(KRT14-cre)1Amc,
Tg(Mef2c-cre)1Blk,
Tg(Mef2c-cre)2Blk,
Tg(Mef2c-cre)#Blk,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Myh11-cre)5013Gko,
Tg(Myh11-cre,-EGFP)2Mik,
Tg(Myh11-cre/ERT2)F31Gko,
Tg(Myh11-dre/ERT2)#Cya,
Tg(Myh11-icre/ERT2)1Soff,
Tg(Myh6-cre)1Xya,
Tg(Myh6-cre)2182Mds,
Tg(Myh6-cre/PGR*)1Mds,
Tg(Myh6-cre/PGR*)6297Mds,
Tg(Myh7-cre)1Zli,
Tg(Myl1-cre)13Nros,
Tg(myl7.L-cre)1118Tmhn,
Tg(MYOD1-cre)M23Glh,
Tg(Myog-cre)1Eno,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Nkx2-5-cre)9Eno,
Tg(Nppa-cre)3Vmc,
Tg(Opn4-cre)#Yau,
Tg(Osr1-cre)4Mrt,
Tg(Pax3-cre)2Joe,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Pf4-icre)Q3Rsko,
Tg(Pitx2-cre/Esr1*)#Hmd,
Tg(Pitx3-cre/ERT2)1Yqd,
Tg(Plp1-cre/ERT)3Pop,
Tg(Postn-icre/ERT2)#Wet,
Tg(Prdm1-cre)1Masu,
Tg(Prg4-cre/ERT2)#Ndy,
Tg(Prrx1-cre)1Cjt,
Tg(Rr437-cre)#Hmd,
Tg(rtetR-tetO-cre)1Mhz,
Tg(S100a4-cre)1Egn,
Tg(Scx-cre)HShuk,
Tg(Sim1-cre)1Lowl,
Tg(Slc1a3-cre/ERT2)45-72Fwp,
Tg(Smarcd3-cre/ERT2)#Bbr,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jjl,
Tg(Tagln-cre)1Jomm,
Tg(Tagln-cre)1Llw,
Tg(Tagln-cre/ERT2)1Feil,
Tg(Tagln-rtTA-cre)1Llw,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(Tbx18-icre)3Fech,
Tg(Tbx1-cre)1Joe,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Ywa,
Tg(Tek-cre)5326Sato,
Tg(Tek-icre/ERT2)1Soff,
Tg(Thy1-cre)1Vln,
Tg(Tnni3-cre/GFP)1Mknn,
Tg(Tnnt2-cre)5Blh,
Tg(Vav1-cre)1Awr,
Tg(Vav1-cre)8Cgp,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt11-cre/ERT2)1Jwng,
Tg(Wt1-cre)1Jbeb,
Tg(WT1-cre)AG11Dbdr,
Thtm1(cre)Te,
Tnni3tm1(EGFP/cre/ERT2)Wtsi,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre/ERT2)Eno,
Viptm1(cre)Zjh,
Wt1tm1(EGFP/cre)Wtp,
Wt1tm2(cre/ERT2)Wtp
(less)
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Images
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J:220957
Fig. 8
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Recombinase Activity
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References
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Analysis Tools