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Foxn1tm3(cre)Nrm - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Foxn1tm3(cre)Nrm
forkhead box N1; targeted mutation 3, Nancy R Manley 		Driver: Foxn1
Type: Targeted (Recombinase)
Synonym: Foxn1ex9cre
Molecular description: An IRES-cre and floxed or frt neo cassette were inserted into the 3' end of exon 9. Insertion was confirmed by PCR of genomic DNA. Removal of the neo cassette by frt-mediated recombination following a cross with Tg(ACTFLPe)9205Dym mice results in a loss of ectopic cre expression but specific expression is retained. RT-PCR was used to confirm that endogenous gene expression was unaffected.
Find mice (IMSR): Mouse Strains: 7 strains available       Cell Lines: 0 lines available
Additional Tissues: Foxn1tm3(cre)Nrm activity also observed in:
branchial arches, hemolymphoid system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:125817 Fig. 2 J:125817 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 78 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory