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Tg(Pf4-icre)Q3Rsko - Embryo-other
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pf4-icre)Q3Rsko
transgene insertion Q3, Radek C Skoda
Driver: Pf4
Type: Transgenic (Recombinase)
Synonym: Pf4-Cre, (Pf4)-Cre, Tg(Cxcl4-cre)Q3Rsko, Tg(Pf4-cre)Q3Rsko
Molecular description: A transgene was created from a BAC where cre-recombinase is driven by the Cxcl4 (Platelet factor 4) promoter. This transgene also contains the Cxcl3, Cxcl5, Ppbp, and Cxcl15 genes. This line has one copy of the transgene inserted with expression restricted to megakaryocytes and platelets, as demonstrated by RT-PCR and Western blotting.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pf4-icre)Q3Rsko activity also observed in:
Tissue Information
Embryo-other Other recombinase alleles with activity in Embryo-other tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 308 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory