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Allele Information
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Allele:
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Tg(Pf4-icre)Q3Rsko
transgene insertion Q3, Radek C Skoda
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Driver: Pf4
Type: Transgenic
(Recombinase)
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Synonym:
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Pf4-Cre, (Pf4)-Cre, Tg(Cxcl4-cre)Q3Rsko, Tg(Pf4-cre)Q3Rsko
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Molecular description:
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A transgene was created from a BAC where cre-recombinase is driven by the Cxcl4 (Platelet factor 4) promoter. This transgene also contains the Cxcl3, Cxcl5, Ppbp, and Cxcl15 genes. This line has one copy of the transgene inserted with expression restricted to megakaryocytes and platelets, as demonstrated by RT-PCR and Western blotting.
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Pf4-icre)Q3Rsko activity also observed in:
adipose tissue,
alimentary system,
cardiovascular system,
cavities & their linings,
embryo-other,
endocrine system,
head,
hemolymphoid system,
integumental system,
limbs,
mesenchyme,
muscle,
nervous system,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system
(less)
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Tissue Information
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Liver & Biliary System
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Other recombinase alleles with activity in Liver & Biliary System tissues:
Abcg2tm1.1(cre/Esr1*)Jvbe,
Albem1(dre/ERT2)Bzsh,
Albtm1(cre/ERT2)Mtz,
Albtm1(cre/ERT2)Smoc,
Aldh1l1em1(cre/ERT2)Nju,
Alpltm1(cre)Nagy,
Aplnrem3(cre/ERT2)Smoc,
Ccktm1.1(cre)Zjh,
Cd34tm1.1(cre/ERT2)Lizg,
Cd40lgtm1.1(icre)Tega,
Cdh5em1(cre/ERT2)Smoc,
Cdh5em1(nigri)Bzsh,
Cdkn2atm1.1(cre)Dvb,
Cdkn2atm1(cre/ERT2)Mkt,
Cdkn2atm2.1(cre/ERT2)Dvb,
Cldn6tm1(cre/ERT2)Dam,
Clutm2(EGFP/cre/ERT2)Wtsi,
Commd10Tg(Vav1-icre)A2Kio,
Crybb1em1(icre)Cln,
Cx3cr1tm1.1(cre)Jung,
Cx3cr1tm2.1(cre/ERT2)Jung,
Ddx4em1(icre)Jobo,
E2f1Tg(Wnt1-cre)2Sor,
Eportm1.1(EGFP/icre)Uk,
Epxtm1.1(cre)Jlee,
Fgf18tm2.2(cre/ERT2)Dor,
Fgf21em1(cre)Mpot,
Flt4tm2.1(cre/ERT2)Sgo,
Foxa2tm1(cre)Heli,
Foxa2tm2.1(cre/Esr1*)Moon,
Gad2tm2(cre)Zjh,
Gata4tm2(cre/ERT2)Ykaw,
Gfi1tm1(cre)Gan,
Glp1rtm1.1(cre)Cors,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc,
Gt(ROSA)26Sortm1.1(CAG-cre)Jphe,
Gt(ROSA)26Sortm13(dreo)Maoh,
Gt(ROSA)26Sortm14.1(Thy1-dre)Maoh,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Gt(ROSA)26Sortm2(cre/ERT2)Brn,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Gt(ROSA)26Sortm5(dre)Dwi,
Gt(ROSA)26Sortm6(dre/PGR*)Dwi,
Gt(ROSA)26Sortm8(CAG-dre/ERT2)Bzsh,
H2az2Tg(Wnt1-cre)11Rth,
Hlfem1(cre/ERT2)Smoc,
Hlfem2(cre/ERT2)Suda,
Hnf4aem1(dre/ERT2)Bzsh,
Hnf4atm1(cre)Sdv,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Igs2tm1(Cdkn1a-cre/ERT2,-EGFP)Mxu,
Ihhem1(Tomm20/mKate2,dre)Xya,
Il25tm2.1(icre)Lky,
Il25tm3.1(cre/ERT2)Lky,
Krt17tm1(cre)Murr,
Krt19tm1(cre/ERT)Ggu,
Lect2em1(cre)Smoc,
Leprtm2(cre)Rck,
Ltftm1(icre)Tdku,
Ly6atm2.1(cre/Esr1*)Jmol,
Lyve1tm1.1(EGFP/cre)Cys,
Lyz2tm1(cre)Ifo,
Mecomem1(cre/ERT2)Suda,
Mecomtm4.1(cre/ERT2)Aspe,
Mfsd2aem1(cre/ERT2)Bzsh,
Mfsd2aem2(cre/ERT2)Bzsh,
Myf5tm3(cre)Sor,
Myh6em2(cre)Smoc,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx2-5tm2(cre)Rph,
Osr2tm2(cre)Jian,
P2ry12em1(icre/ERT2)Tda,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Pdx1tm1.1(flpo)Most,
Piezo1em2(cre/ERT2)Smoc,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Pms2tm2(cre)Lisk,
Prlrtm1.1(cre)Uboe,
Ptf1atm1.1(cre)Cvw,
Rbpmsem1(cre/ERT2)Yzhe,
Runx1tm1(cre/Esr1*)Ims,
Shhtm1(EGFP/cre)Cjt,
Sox17tm1(icre)Heli,
Sox17tm2.1(icre)Heli,
Sox17tm4.1(icre/ERT2)Heli,
Sox2tm1.1(cre/ERT2)Ykaw,
Speer6-ps1Tg(Alb-cre)21Mgn,
Spink1tm3(cre)Kymm,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Taglntm2(cre)Yec,
Tbx21tm1.1(cre/ERT2)Ayr,
Tbx3em1(cre/ERT2)Toyo,
Tekem1(dre)Bzsh,
Tektm1.1(icre/Esr1*)Hrr,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(ACTA1-cre)79Jme,
Tg(ACTB-cre)1Tes,
Tg(Acvrl1-cre)B1Spo,
Tg(Alb1-cre)1Dlr,
Tg(Alb1-cre)7Gsc,
Tg(Alb-cre/ERT2)#Nor,
Tg(Aldh1l1-cre/ERT2)02Kan,
Tg(Amy2-cre)1Herr,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Car1-cre)5Flt,
Tg(Ccr2-cre/ERT2)12Kuan,
Tg(CD2-icre)4Kio,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)1Nmoc,
Tg(Cdh5-cre)1Spe,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Chst4-cre)1Hkwa,
Tg(Clec4g-icre)1.1Sgoe,
Tg(CMV-cre)1Cgn,
Tg(Col1a2-cre)23Angl,
Tg(Csf1r-cre/Esr1*)1Jwp,
Tg(Csf1r-icre)1Jwp,
Tg(Ctgf-cre)2Aibs,
Tg(Ctsk-cre)8Rda,
Tg(Cyp17a1-icre)AJako,
Tg(Cyp19a1-cre)5909Gle,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp1a1-cre/ERT)1Dwi,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Epo-cre)44Mym,
Tg(Etv2-cre)15508Djg,
Tg(Fabp1-cre)1Jig,
Tg(Fabp4-cre)1Rev,
Tg(Fgfr3-icre/ERT2)4-2Wdr,
Tg(Foxl1-cre)1Khk,
Tg(Gata1-cre)1Sho,
Tg(GATA5-cre)1Krc,
Tg(GFAP-cre)25Mes,
Tg(Glp1r-icre)#Fmgb,
Tg(Grik4-cre)G32-4Stl,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hspa2-cre)1Eddy,
Tg(Il7-cre)CRche,
Tg(Ins2-cre)25Mgn,
Tg(Islr-cre/ERT2)#Tobe,
Tg(Itga2b-cre)AParl,
Tg(Itga2b-cre)NE1/21Emam,
Tg(Itgax-cre)1-1Reiz,
Tg(Kap-icre)29066/2Sig,
Tg(Kdr-cre)15962Brei,
Tg(KRT14-cre)1Amc,
Tg(KRT18-cre/ERT2)1Rgo,
Tg(Krt19-icre)2Hirt,
Tg(Krt8-cre/ERT2,-GFP)1Xin,
Tg(Lck-icre)3779Nik,
Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho,
Tg(Lrat-cre)1Rshw,
Tg(Mafg-Nrf2/cre,-EGFP)737Hozu,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Mx1-cre)29-4Her,
Tg(MYOD1-cre)M23Glh,
Tg(Ncr1-cre/ERT2)#Lll,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Nkx2-5-cre)9Eno,
Tg(Nrp2-cre,-EGFP)#Qsch,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Prdm1-cre)1Masu,
Tg(Prox1-cre/ERT2)1Tmak,
Tg(Prrx1-cre)1Cjt,
Tg(REN-cre)1Haca,
Tg(Retnla-cre)#Voeh,
Tg(Runx1/Hspa1a-cre/ERT2)#Itoy,
Tg(S100a4-cre)1Egn,
Tg(SERPINA1-cre)1Arge,
Tg(SERPINA1-cre/ERT)1Ipc,
Tg(Sim1-cre)1Lowl,
Tg(Spp1-icre/ERT2)#Lecl,
Tg(Stab2-icre)1.2Cger,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jjl,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre)1Ywa,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Arnd,
Tg(Tek-icre/ERT2)1Soff,
Tg(tetO-cre)LC1Bjd,
Tg(Thy1-cre)1Vln,
Tg(Thy1-cre)703Vaw,
Tg(Tie1-cre)9Ref,
Tg(Tshb-cre)4Sac,
Tg(Ttr-cre/Esr1*)1Vco,
Tg(VAV1-cre)1Graf,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Zp3-cre)3Mrt,
Tlr2tm1(cre)Dfil,
Tmprss2tm1.1(cre/ERT2)Ychen,
Tnfrsf19tm1.1(cre/ERT2)Cle,
Trem2em1(cre)Jddl,
Twist2tm1.1(cre)Dor,
Vil1em1(flpo)Lbrl,
Wt1tm1(EGFP/cre)Wtp
(less)
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Recombinase Activity
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References
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