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Tg(Pf4-icre)Q3Rsko - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pf4-icre)Q3Rsko
transgene insertion Q3, Radek C Skoda 		Driver: Pf4
Type: Transgenic (Recombinase)
Synonym: Pf4-Cre, (Pf4)-Cre, Tg(Cxcl4-cre)Q3Rsko, Tg(Pf4-cre)Q3Rsko
Molecular description: A transgene was created from a BAC where cre-recombinase is driven by the Cxcl4 (Platelet factor 4) promoter. This transgene also contains the Cxcl3, Cxcl5, Ppbp, and Cxcl15 genes. This line has one copy of the transgene inserted with expression restricted to megakaryocytes and platelets, as demonstrated by RT-PCR and Western blotting.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pf4-icre)Q3Rsko activity also observed in:
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Images
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J:184579 Full Image
Fig. Pf4 Kidney P56 J:184579 Full Image
Fig. Pf4 Kidney P7 J:184579 Full Image
Fig. Sst Bladder P56
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 308 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory