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Leprtm2(cre)Rck - Embryo-other
Recombinase Activity Detail
Allele Information
Allele:
Leprtm2(cre)Rck
leptin receptor; targeted mutation 2, Jeffrey M Friedman 		Driver: Lepr
Type: Targeted (Recombinase)
Synonym: LeprB-Cre, LepRbCre, LepRb-IRES-Cre, Leprcre, ObRb-Cre, Obrb-IRES-Cre
Molecular description: A cre recombinase expression cassette containing an IRES domain and a FRT-flanked neomcyin cassette was placed immediately downstream of the stop codon for the gene. Flp-mediated recombination removed the FRT-flanked neo cassette. Cre expression in the hypothalamus was confirmed by use of a virus containing a cre-dependent reporter gene.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Leprtm2(cre)Rck activity also observed in:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 151 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory