Mapt<tm2(cre)Aha> - Renal & Urinary System Recombinase Activity Detail MGI Mouse

Mapt^tm2(cre)Aha - Renal & Urinary System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Mapt^tm2(cre)Aha
microtubule-associated protein tau; targeted mutation 2, Akihiro Harada

Driver: Mapt
Type: Targeted (Recombinase)

Synonym:

tau-Cre

Molecular description:

A cre gene with a nuclear localization signal followed by an frt-flanked neo cassette was inserted immediately after the start methionine. Cre function is dectected in neurons of almost all areas of the brain with only granule cells in the caudal part of the cerebellum not exhbiting cre function. Other organs such as the liver, kidney and intestine do not exhibit cre function.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Mapt^tm2(cre)Aha activity also observed in:
head, nervous system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

7 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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