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Tg(Pdgfb-icre/ERT2,-EGFP)1Frut - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut
transgene insertion 1, Marcus Fruttiger 		Driver: Pdgfb
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Pdgfb-iCreER, Pdgfb-iCre-ERT2-Egfp, Tg(Pdgfb-cre/ERT2)1Frut, Tg(Pdgfb-cre/ESR1)1Frut
Molecular description: The mouse Pdgfb promoter was used to drive inducible expression of an improved cre gene fused to ERT2 and followed by an IRES-EGFP then an frt-flanked chloramphenicol resistance gene in vascular endothelium. The PAC used (RP21-629-J8) contains the entire Pdgfb gene with the cre cassette inserted immediately following the start methionine codon. No line information was given.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pdgfb-icre/ERT2,-EGFP)1Frut activity also observed in:
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:135315 Fig. 2 J:135315 Fig. 3 J:135315 Fig. 4 J:135315 Fig. 5 J:135315 Fig. 6 J:135315 Fig. 8 J:228184 Fig. 2 J:228184 Fig. 4
J:228184 Fig. S6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 154 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory