Wt1<tm2(cre/ERT2)Wtp> - Cavities & Their Linings Recombinase Activity Detail MGI Mouse

Wt1^{tm2(cre/ERT2)Wtp} - Cavities & Their Linings
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Wt1^{tm2(cre/ERT2)Wtp}
WT1 transcription factor; targeted mutation 2, William T Pu

Driver: Wt1
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Wt1^CreERT2, Wt1^iCre, Wt1^{tm2(cre/ESR1)Wtp}

Molecular description:

Exon 1 was replaced with an inducible cre ESR1 (ERT2) fusion followed by an FRT-flanked neo cassette. Testing in 2023 by the investigator's laboratory, indicates that the FRT-flanked neo has not been removed as reported.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Wt1^{tm2(cre/ERT2)Wtp} activity also observed in:
cardiovascular system, muscle, respiratory system

Tissue Information

Cavities & Their Linings

Other recombinase alleles with activity in Cavities & Their Linings tissues:

Alpl^tm1(cre)Nagy, Atoh8^{tm1(EGFP/cre)Gasa}, Bhlhe41^em1(cre)Cya, Calb2^tm1(cre)Zjh ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

89 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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