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Tg(Cyp17a1-icre)AJako - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cyp17a1-icre)AJako
transgene insertion A, CheMyong Ko
Driver: Cyp17a1
Type: Transgenic (Recombinase)
Synonym: Cyp17iCre, TCCre, Tg(Cyp17a1-cre)ACmk
Molecular description: The promoter was used to drive expression of a codon improved cre in the theca/interstitial cells of the ovary and Leydig cells of the testes. Three lines (lines A, B and C) were created. While all lines exhibit gonadal expression, line B and C exhibit extra-gonadal expression.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cyp17a1-icre)AJako activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:138920 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory