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Tg(Nr2e1-cre/ERT2)1Gsc - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nr2e1-cre/ERT2)1Gsc
transgene insertion 1, Gunther Schutz 		Driver: Nr2e1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Tlx-CreERT2
Molecular description: This transgene consists of modified BAC containing the entire coding region of the Nr2e1 gene including flanking regulatory sequences 104 kb upstream and 30 kb downstream, and drives expression of a tamoxifen-inducible form of cre recombinase fusion protein which replaces part of exon 1 of the Nr2e1 gene. 6 lines were generated of which 3 lines are further analyzed. All three lines showed tamoxifen-inducible Cre activity in the developing forebrain. This is a representative record for all 3 lines.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nr2e1-cre/ERT2)1Gsc activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory